Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment
Zainab Lafi
1
,
Sina Matalqah
1
,
Ebaa Abu-Saleem
1
,
Nisreen Asha
2
,
Hala Mhaidat
3
,
Sherine Asha
4
,
Lara Al-Nashash
1
,
Hussein S. Janabi
1
3
King Abdullah University Hospital, Irbid, Jordan
|
Publication type: Journal Article
Publication date: 2024-12-09
scimago Q1
wos Q2
SJR: 0.916
CiteScore: 5.3
Impact factor: 3.5
ISSN: 13570560, 1559131X
PubMed ID:
39653960
Abstract
The integration of nanotechnology into cancer treatment has revolutionized chemotherapy, boosted its effectiveness while reduced side effects. Among the various nanotherapeutic approaches, metal–organic frameworks (MOFs) stand out as promising carriers for targeted chemotherapy, with the added benefit of enabling combination therapies. MOFs, composed of metal ions or clusters linked by coordination bonds, tackle critical issues in traditional cancer treatments, such as poor stability, limited efficacy, and severe side effects. Their key advantages include customizable size and shape, diverse compositions, controlled porosity, large surface areas, ease of modification, and biocompatibility. This review highlights recent advancements in the use of MOFs for cancer therapy, showcasing their role in both monotherapies and combination strategies. Additionally, it explores the future potential and challenges of MOF-based platforms in tumor treatment.
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Metrics
8
Total citations:
8
Citations from 2024:
7
(87.5%)
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GOST
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Lafi Z. et al. Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment // Medical Oncology. 2024. Vol. 42. No. 1. 26
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Lafi Z., Matalqah S., Abu-Saleem E., Asha N., Mhaidat H., Asha S., Al-Nashash L., Janabi H. S. Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment // Medical Oncology. 2024. Vol. 42. No. 1. 26
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TY - JOUR
DO - 10.1007/s12032-024-02567-3
UR - https://link.springer.com/10.1007/s12032-024-02567-3
TI - Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment
T2 - Medical Oncology
AU - Lafi, Zainab
AU - Matalqah, Sina
AU - Abu-Saleem, Ebaa
AU - Asha, Nisreen
AU - Mhaidat, Hala
AU - Asha, Sherine
AU - Al-Nashash, Lara
AU - Janabi, Hussein S.
PY - 2024
DA - 2024/12/09
PB - Springer Nature
IS - 1
VL - 42
PMID - 39653960
SN - 1357-0560
SN - 1559-131X
ER -
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BibTex (up to 50 authors)
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@article{2024_Lafi,
author = {Zainab Lafi and Sina Matalqah and Ebaa Abu-Saleem and Nisreen Asha and Hala Mhaidat and Sherine Asha and Lara Al-Nashash and Hussein S. Janabi},
title = {Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment},
journal = {Medical Oncology},
year = {2024},
volume = {42},
publisher = {Springer Nature},
month = {dec},
url = {https://link.springer.com/10.1007/s12032-024-02567-3},
number = {1},
pages = {26},
doi = {10.1007/s12032-024-02567-3}
}