Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents
1
Division of Pharmaceutical Chemistry, Department of Pharmacy, IEC College of Engineering and Technology, Greater Noida, India
|
2
Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, India
|
3
Maharaja Surajmal Institute of Pharmacy, Janak Puri, India
|
Publication type: Journal Article
Publication date: 2013-01-01
scimago Q3
wos Q3
SJR: 0.315
CiteScore: 3.0
Impact factor: 2.0
ISSN: 09743626, 09737103, 02534134
General Chemistry
Abstract
Twelve compounds belonging to series N-[3-chloro-2-oxo-4-(substituted)phenylazetidin-1-yl]-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide (5a–l) were synthesized. These compounds were evaluated for their in vitro antibacterial against E. coli, S. aureus, K. pneumoniae, P. aeruginosa and antifungal activity against C. albicans, A. niger and A. flavus by cup-plate method. Structures of all the newly synthesized compounds were confirmed by their spectral data interpretation. Compound 5g having p-dimethylaminophenyl group on 4-position of azetidinone ring attached to N-atom of acetamido group on 1-position of 3-methyl-1H-quinoxaline-2-one, was found to be active against all the bacterial and fungal strains under investigation.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
|
|
|
Mini-Reviews in Medicinal Chemistry
1 publication, 25%
|
|
|
ChemInform
1 publication, 25%
|
|
|
ChemMedChem
1 publication, 25%
|
|
|
Bioorganic Chemistry
1 publication, 25%
|
|
|
1
|
Publishers
|
1
2
|
|
|
Wiley
2 publications, 50%
|
|
|
Bentham Science Publishers Ltd.
1 publication, 25%
|
|
|
Elsevier
1 publication, 25%
|
|
|
1
2
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
4
Total citations:
4
Citations from 2024:
2
(50%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Kumar S. et al. Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents // Journal of Chemical Sciences. 2013. Vol. 125. No. 1. pp. 129-139.
GOST all authors (up to 50)
Copy
Kumar S., Kumar N., Drabu S., Minhaj M. A. Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents // Journal of Chemical Sciences. 2013. Vol. 125. No. 1. pp. 129-139.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s12039-012-0354-x
UR - https://doi.org/10.1007/s12039-012-0354-x
TI - Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents
T2 - Journal of Chemical Sciences
AU - Kumar, Shiv
AU - Kumar, Nitin
AU - Drabu, Sushma
AU - Minhaj, Md Akram
PY - 2013
DA - 2013/01/01
PB - Springer Nature
SP - 129-139
IS - 1
VL - 125
SN - 0974-3626
SN - 0973-7103
SN - 0253-4134
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2013_Kumar,
author = {Shiv Kumar and Nitin Kumar and Sushma Drabu and Md Akram Minhaj},
title = {Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents},
journal = {Journal of Chemical Sciences},
year = {2013},
volume = {125},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s12039-012-0354-x},
number = {1},
pages = {129--139},
doi = {10.1007/s12039-012-0354-x}
}
Cite this
MLA
Copy
Kumar, Shiv, et al. “Synthesis of 2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide-based azetidinone derivatives as potent antibacterial and antifungal agents.” Journal of Chemical Sciences, vol. 125, no. 1, Jan. 2013, pp. 129-139. https://doi.org/10.1007/s12039-012-0354-x.