Traits and Biomarkers for Addiction Risk in Schizophrenia
3
Publication type: Journal Article
Publication date: 2017-02-22
scimago Q1
wos Q1
SJR: 1.784
CiteScore: 6.8
Impact factor: 4.6
ISSN: 21962952
Clinical Psychology
Psychiatry and Mental health
Abstract
The most common addictions in schizophrenia include tobacco, cannabis, alcohol, stimulants/recreational drugs, and gambling. This review discusses the multifactorial risk factors for addictions in people with schizophrenia. Several hypotheses have been proposed to explain addiction comorbidity in schizophrenia, and potential biomarkers conferring addiction risk in patients have been identified (e.g., catechol-O-methyltransferase (COMT), brain-derived neurotrophic factor (BDNF), v-akt murine thymoma viral oncogene homolog 1 (AKT1), cortical inhibition, working memory). Neurotransmitter systems including dopaminergic, glutamatergic, and GABAergic pathways are associated with the pathophysiology of both schizophrenia and addictions. Developing effective treatments for schizophrenia and comorbid addictions is warranted and should involve further studies of neurobiological underpinnings of addiction risk in schizophrenia.
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10
Total citations:
10
Citations from 2024:
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(10%)
Cite this
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MLA
Cite this
GOST
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Kozak K. et al. Traits and Biomarkers for Addiction Risk in Schizophrenia // Current Addiction Reports. 2017. Vol. 4. No. 1. pp. 14-24.
GOST all authors (up to 50)
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Kozak K., Barr M. S., George T. P. Traits and Biomarkers for Addiction Risk in Schizophrenia // Current Addiction Reports. 2017. Vol. 4. No. 1. pp. 14-24.
Cite this
RIS
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TY - JOUR
DO - 10.1007/s40429-017-0130-6
UR - https://doi.org/10.1007/s40429-017-0130-6
TI - Traits and Biomarkers for Addiction Risk in Schizophrenia
T2 - Current Addiction Reports
AU - Kozak, Karolina
AU - Barr, Mera S.
AU - George, Tony P.
PY - 2017
DA - 2017/02/22
PB - Springer Nature
SP - 14-24
IS - 1
VL - 4
SN - 2196-2952
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2017_Kozak,
author = {Karolina Kozak and Mera S. Barr and Tony P. George},
title = {Traits and Biomarkers for Addiction Risk in Schizophrenia},
journal = {Current Addiction Reports},
year = {2017},
volume = {4},
publisher = {Springer Nature},
month = {feb},
url = {https://doi.org/10.1007/s40429-017-0130-6},
number = {1},
pages = {14--24},
doi = {10.1007/s40429-017-0130-6}
}
Cite this
MLA
Copy
Kozak, Karolina, et al. “Traits and Biomarkers for Addiction Risk in Schizophrenia.” Current Addiction Reports, vol. 4, no. 1, Feb. 2017, pp. 14-24. https://doi.org/10.1007/s40429-017-0130-6.