Adrenochrome formation during photochemical decomposition of “caged” epinephrine derivatives
Ezhena S. Starodubtseva
1
,
Tatyana Yu Karogodina
1, 2
,
Mikhail A Panfilov
2
,
Dmitriy G Sheven
3
,
Olga Yu Selyutina
4
,
Alexey Yu Vorobev
1, 2
,
Publication type: Journal Article
Publication date: 2024-11-29
scimago Q2
wos Q2
SJR: 0.629
CiteScore: 5.1
Impact factor: 3.2
ISSN: 1474905X, 14749092
PubMed ID:
39612097
Abstract
Control of biological activity with light is a fascinating idea. “Caged” compounds, molecules modified with photolabile protecting group, are one of the instruments for this purpose. Adrenergic receptors are essential regulators of neuronal, endocrine, cardiovascular, vegetative, and metabolic functions. These receptors are largely used as pharmacologic targets. Photolabile “caged” analogs of adrenergic receptor agonists has been reported more than 30 years ago. We report that the photolysis of epinephrine analogs, apart from liberation of the epinephrine, is accompanied by a formation of significant amount of adrenochrome, a compound with neuro- and cardiotoxic effect.
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Total citations:
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Citations from 2024:
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(100%)
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Starodubtseva E. S. et al. Adrenochrome formation during photochemical decomposition of “caged” epinephrine derivatives // Photochemical and Photobiological Sciences. 2024. Vol. 23. No. 12. pp. 2265-2268.
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Starodubtseva E. S., Karogodina T. Yu., Panfilov M. A., Sheven D. G., Selyutina O. Yu., Vorobev A. Yu., Moskalensky A. E. Adrenochrome formation during photochemical decomposition of “caged” epinephrine derivatives // Photochemical and Photobiological Sciences. 2024. Vol. 23. No. 12. pp. 2265-2268.
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RIS
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TY - JOUR
DO - 10.1007/s43630-024-00665-9
UR - https://link.springer.com/10.1007/s43630-024-00665-9
TI - Adrenochrome formation during photochemical decomposition of “caged” epinephrine derivatives
T2 - Photochemical and Photobiological Sciences
AU - Starodubtseva, Ezhena S.
AU - Karogodina, Tatyana Yu
AU - Panfilov, Mikhail A
AU - Sheven, Dmitriy G
AU - Selyutina, Olga Yu
AU - Vorobev, Alexey Yu
AU - Moskalensky, Alexander E.
PY - 2024
DA - 2024/11/29
PB - Springer Nature
SP - 2265-2268
IS - 12
VL - 23
PMID - 39612097
SN - 1474-905X
SN - 1474-9092
ER -
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BibTex (up to 50 authors)
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@article{2024_Starodubtseva,
author = {Ezhena S. Starodubtseva and Tatyana Yu Karogodina and Mikhail A Panfilov and Dmitriy G Sheven and Olga Yu Selyutina and Alexey Yu Vorobev and Alexander E. Moskalensky},
title = {Adrenochrome formation during photochemical decomposition of “caged” epinephrine derivatives},
journal = {Photochemical and Photobiological Sciences},
year = {2024},
volume = {23},
publisher = {Springer Nature},
month = {nov},
url = {https://link.springer.com/10.1007/s43630-024-00665-9},
number = {12},
pages = {2265--2268},
doi = {10.1007/s43630-024-00665-9}
}
Cite this
MLA
Copy
Starodubtseva, Ezhena S., et al. “Adrenochrome formation during photochemical decomposition of “caged” epinephrine derivatives.” Photochemical and Photobiological Sciences, vol. 23, no. 12, Nov. 2024, pp. 2265-2268. https://link.springer.com/10.1007/s43630-024-00665-9.
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