The Japanese Journal of Human Genetics, volume 34, issue 4, pages 307-311
Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 byin situ hybridization with biotinylated DNA probe
Ei-ichi Takahashi
1
,
TADA-AKI HORI
1
,
Jeanne B. Lawrence
2
,
John McNeil
2
,
Robert H. Singer
2
,
Peter O'Connell
3
,
Mark Leppert
3
,
Ray White
3
Publication type: Journal Article
Publication date: 1989-12-01
SJR: —
CiteScore: —
Impact factor: —
ISSN: 00215074, 09168478
PubMed ID:
2634791
Genetics (clinical)
Abstract
We have made a regional assignment of the type II collagen gene (COL2A1) on human chromosome 12 by means of anin situ hybridization technique with a biotinylated DNA probe. The precise localization of the signal was mapped to the band 12q13.1-q13.2. This result was in agreement with the previous mapping by isotopicin situ hybridization technique (12q13.1-q13.2), but not with the result of Southern hybridization analysis using somatic cell hybrids (12q14.3).
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