Synthesis and study of antimicrobial activity of quaternary ammonium benzofuroxan salts
Elena Chugunova
1
,
Nurgali I Akylbekov
2
,
Essam M Mahrous
2
,
Alexandra D Voloshina
1
,
Natalia V Kulik
1
,
Vladimir V Zobov
1
,
Anna G Strelnik
1
,
Alexey B. Dobrynin
1
,
Alexander R Burilov
1
Publication type: Journal Article
Publication date: 2017-12-06
scimago Q3
wos Q3
SJR: 0.321
CiteScore: 3.4
Impact factor: 1.9
ISSN: 00269247, 14344475
General Chemistry
Abstract
It was found that quaternary ammonium salts of benzofuroxan based on o-, m-, and p-dibromoxylenes are formed as a mixture of two tautomers. Only one bromomethyl group participates in the quaternization of benzofuroxan with different dibromoxylenes. Bacteriostatic activity of the most active mixture of tautomers was two and four times higher than the reference drug, chloramphenicol, with respect to Staphylococcus aureus 209p and Bacillus cereus 8035, correspondingly. Hemolysis of these compounds does not exceed 1%, i.e., such compounds are not toxic.
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Total citations:
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Citations from 2024:
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GOST
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Chugunova E. et al. Synthesis and study of antimicrobial activity of quaternary ammonium benzofuroxan salts // Monatshefte fur Chemie. 2017. Vol. 149. No. 1. pp. 119-126.
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Chugunova E., Akylbekov N. I., Mahrous E. M., Voloshina A. D., Kulik N. V., Zobov V. V., Strelnik A. G., Gerasimova T. P., Dobrynin A. B., Burilov A. R. Synthesis and study of antimicrobial activity of quaternary ammonium benzofuroxan salts // Monatshefte fur Chemie. 2017. Vol. 149. No. 1. pp. 119-126.
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RIS
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TY - JOUR
DO - 10.1007/s00706-017-2052-3
UR - https://doi.org/10.1007/s00706-017-2052-3
TI - Synthesis and study of antimicrobial activity of quaternary ammonium benzofuroxan salts
T2 - Monatshefte fur Chemie
AU - Chugunova, Elena
AU - Akylbekov, Nurgali I
AU - Mahrous, Essam M
AU - Voloshina, Alexandra D
AU - Kulik, Natalia V
AU - Zobov, Vladimir V
AU - Strelnik, Anna G
AU - Gerasimova, Tatiana P
AU - Dobrynin, Alexey B.
AU - Burilov, Alexander R
PY - 2017
DA - 2017/12/06
PB - Springer Nature
SP - 119-126
IS - 1
VL - 149
SN - 0026-9247
SN - 1434-4475
ER -
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BibTex (up to 50 authors)
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@article{2017_Chugunova,
author = {Elena Chugunova and Nurgali I Akylbekov and Essam M Mahrous and Alexandra D Voloshina and Natalia V Kulik and Vladimir V Zobov and Anna G Strelnik and Tatiana P Gerasimova and Alexey B. Dobrynin and Alexander R Burilov},
title = {Synthesis and study of antimicrobial activity of quaternary ammonium benzofuroxan salts},
journal = {Monatshefte fur Chemie},
year = {2017},
volume = {149},
publisher = {Springer Nature},
month = {dec},
url = {https://doi.org/10.1007/s00706-017-2052-3},
number = {1},
pages = {119--126},
doi = {10.1007/s00706-017-2052-3}
}
Cite this
MLA
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Chugunova, Elena, et al. “Synthesis and study of antimicrobial activity of quaternary ammonium benzofuroxan salts.” Monatshefte fur Chemie, vol. 149, no. 1, Dec. 2017, pp. 119-126. https://doi.org/10.1007/s00706-017-2052-3.
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