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Amino Acids

, том 37 , издание 2 , страницы 383-388

Synthesis, antioxidative and antiviral activity of hydroxycinnamic acid amides of thiazole containing amino acid

Ivanka Stankova ¹

Kiril Chuchkov ¹

Stoyan Shishkov ²

Kalina Kostova ²

Luchia Mukova ³

Angel S Galabov ³

Скрыть аффилиации авторов Показать аффилиации авторов: 3 аффилиации

Department of Chemistry, South-West University “Neofit Rilski”, Blagoevgrad, Bulgaria |

Laboratory of Virology, Faculty of Biology, St. Kl. Ohridski Sofia University, Sofia, Bulgaria |

Bulgarian Academy of Sciences, The Stephan Angeloff Institute of Microbiology, Sofia, Bulgaria |

Тип публикации: Journal Article

Дата публикации: 2008-10-14

Springer Nature

Amino Acids

scimago Q1

wos Q3

БС2

SJR: 0.803

CiteScore: 6.8

Impact factor: 2.4

ISSN: 09394451, 14382199

DOI: 10.1007/s00726-008-0165-z

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PubMed ID: 18853101

Organic Chemistry

Biochemistry

Clinical Biochemistry

Краткое описание

The synthesis and the biological (antioxidant and antiviral) activities of novel hydroxycinnamic acid amides of a thiazole containing TFA.valine-4-carboxylic acid ethyl ester are reported. The amides have been synthesized from p-coumaric, ferulic and sinapic acids with the corresponding TFA.valine-thiazole-4-carboxylic acid ethyl ester using the coupling reagent N-ethyl-N′-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) and 4-(dimethylamino) pyridine (DMAP) as a catalyst. The antioxidant properties of the newly synthesized amides have been studied for then antioxidative activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH)* test. The newly synthesized compounds have been tested against the replication in vitro of influenza virus A (H3N2) and human herpes virus 1 and 2 (HSV-1 and HSV-2).

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Stankova I. et al. Synthesis, antioxidative and antiviral activity of hydroxycinnamic acid amides of thiazole containing amino acid // Amino Acids. 2008. Vol. 37. No. 2. pp. 383-388.

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Stankova I., Chuchkov K., Shishkov S., Kostova K., Mukova L., Galabov A. S. Synthesis, antioxidative and antiviral activity of hydroxycinnamic acid amides of thiazole containing amino acid // Amino Acids. 2008. Vol. 37. No. 2. pp. 383-388.

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TY - JOUR

DO - 10.1007/s00726-008-0165-z

UR - https://doi.org/10.1007/s00726-008-0165-z

TI - Synthesis, antioxidative and antiviral activity of hydroxycinnamic acid amides of thiazole containing amino acid

T2 - Amino Acids

AU - Stankova, Ivanka

AU - Chuchkov, Kiril

AU - Shishkov, Stoyan

AU - Kostova, Kalina

AU - Mukova, Luchia

AU - Galabov, Angel S

PY - 2008

DA - 2008/10/14

PB - Springer Nature

SP - 383-388

IS - 2

VL - 37

PMID - 18853101

SN - 0939-4451

SN - 1438-2199

ER -

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@article{2008_Stankova,

author = {Ivanka Stankova and Kiril Chuchkov and Stoyan Shishkov and Kalina Kostova and Luchia Mukova and Angel S Galabov},

title = {Synthesis, antioxidative and antiviral activity of hydroxycinnamic acid amides of thiazole containing amino acid},

journal = {Amino Acids},

year = {2008},

volume = {37},

publisher = {Springer Nature},

month = {oct},

url = {https://doi.org/10.1007/s00726-008-0165-z},

number = {2},

pages = {383--388},

doi = {10.1007/s00726-008-0165-z}

}

MLA

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Stankova, Ivanka, et al. “Synthesis, antioxidative and antiviral activity of hydroxycinnamic acid amides of thiazole containing amino acid.” Amino Acids, vol. 37, no. 2, Oct. 2008, pp. 383-388. https://doi.org/10.1007/s00726-008-0165-z.

Издатель

Springer Nature

Журнал

Amino Acids

scimago Q1

wos Q3

БС2

SJR

0.803

CiteScore

6.8

Impact factor

2.4

ISSN

09394451 (Print)

14382199 (Electronic)