Annals of Biomedical Engineering, volume 37, issue 10, pages 1934-1959

Investigating Biological Processes at the Single Molecule Level Using Luminescent Quantum Dots

THOMAS PONS 1
Hedi Mattoussi 2
2
 
Division of Optical Sciences, US Naval Research Laboratory, Washington, USA
Publication typeJournal Article
Publication date2009-06-12
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor3.8
ISSN00906964, 15216047, 15739686
Biomedical Engineering
Abstract
In this report we summarize the progress made in the past several years on the use of luminescent QDs to probe biological processes at the single molecule level. We start by providing a quick overview of the basic properties of semiconductor nanocrystals, including synthetic routes, surface-functionalization strategies, along with the main attributes of QDs that are of direct relevance to single molecule studies based on fluorescence detection. We then detail some valuable insights into specific biological processes gained using single QDs. These include progress made in probing biomolecular interactions, tracking of protein receptors both in vitro and in live cells, and single particle resonance energy transfer. We will also discuss the advantages offered and limitations encountered by single QD fluorescence as an investigative tool in biology.

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PONS T., Mattoussi H. Investigating Biological Processes at the Single Molecule Level Using Luminescent Quantum Dots // Annals of Biomedical Engineering. 2009. Vol. 37. No. 10. pp. 1934-1959.
GOST all authors (up to 50) Copy
PONS T., Mattoussi H. Investigating Biological Processes at the Single Molecule Level Using Luminescent Quantum Dots // Annals of Biomedical Engineering. 2009. Vol. 37. No. 10. pp. 1934-1959.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1007/s10439-009-9715-0
UR - https://doi.org/10.1007/s10439-009-9715-0
TI - Investigating Biological Processes at the Single Molecule Level Using Luminescent Quantum Dots
T2 - Annals of Biomedical Engineering
AU - PONS, THOMAS
AU - Mattoussi, Hedi
PY - 2009
DA - 2009/06/12 00:00:00
PB - Springer Nature
SP - 1934-1959
IS - 10
VL - 37
SN - 0090-6964
SN - 1521-6047
SN - 1573-9686
ER -
BibTex |
Cite this
BibTex Copy
@article{2009_PONS,
author = {THOMAS PONS and Hedi Mattoussi},
title = {Investigating Biological Processes at the Single Molecule Level Using Luminescent Quantum Dots},
journal = {Annals of Biomedical Engineering},
year = {2009},
volume = {37},
publisher = {Springer Nature},
month = {jun},
url = {https://doi.org/10.1007/s10439-009-9715-0},
number = {10},
pages = {1934--1959},
doi = {10.1007/s10439-009-9715-0}
}
MLA
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MLA Copy
PONS, THOMAS, and Hedi Mattoussi. “Investigating Biological Processes at the Single Molecule Level Using Luminescent Quantum Dots.” Annals of Biomedical Engineering, vol. 37, no. 10, Jun. 2009, pp. 1934-1959. https://doi.org/10.1007/s10439-009-9715-0.
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