Springer Nature
Bulletin of Experimental Biology and Medicine
,  volume 154 ,  issue 2 ,  pages 274-277

Visualization of Experimental Glioma C6 by MRI with Magnetic Nanoparticles Conjugated with Monoclonal Antibodies to Vascular Endothelial Growth Factor

M A Abakumov 1
, 
S A Shein 1
, 
H Vishvasrao 2
, 
N V Nukolova 3
, 
M Sokolski Papkov 2
, 
T O Sandalova 1
, 
I L Gubskii 1
, 
N F Grinenko 2
, 
A.V. KABANOV 2, 4
, 
V. P. Chekhonin 1, 3
1
 
2
 
3
 
4
 
Publication type: Journal Article
Publication date: 2012-12-02
Springer Nature
scimago Q3
wos Q4
SJR: 0.277
CiteScore: 1.5
Impact factor: 0.6
ISSN: 00074888, 15738221, 03659615, 24131008
General Biochemistry, Genetics and Molecular Biology
General Medicine
Abstract
We developed a method for obtaining iron oxide nanoparticles and their conjugation with monoclonal antibodies to vascular endothelial growth factor. The resultant vector nanoparticles were low-toxic and the antibodies retained their immunochemical activity after conjugation. The study was carried out on rats with intracranial glioma C6 on day 14 after its implantation. The intravenously injected nanoparticles visualized the brain tumor in contrast to nanoparticles conjugated with nonspecific immunoglobulins that did not accumulate in the tumor.
Found 
Found 

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GOST Copy
Abakumov M. A. et al. Visualization of Experimental Glioma C6 by MRI with Magnetic Nanoparticles Conjugated with Monoclonal Antibodies to Vascular Endothelial Growth Factor // Bulletin of Experimental Biology and Medicine. 2012. Vol. 154. No. 2. pp. 274-277.
GOST all authors (up to 50) Copy
Abakumov M. A., Shein S. A., Vishvasrao H., Nukolova N. V., Sokolski Papkov M., Sandalova T. O., Gubskii I. L., Grinenko N. F., KABANOV A., Chekhonin V. P. Visualization of Experimental Glioma C6 by MRI with Magnetic Nanoparticles Conjugated with Monoclonal Antibodies to Vascular Endothelial Growth Factor // Bulletin of Experimental Biology and Medicine. 2012. Vol. 154. No. 2. pp. 274-277.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s10517-012-1929-8
UR - https://doi.org/10.1007/s10517-012-1929-8
TI - Visualization of Experimental Glioma C6 by MRI with Magnetic Nanoparticles Conjugated with Monoclonal Antibodies to Vascular Endothelial Growth Factor
T2 - Bulletin of Experimental Biology and Medicine
AU - Abakumov, M A
AU - Shein, S A
AU - Vishvasrao, H
AU - Nukolova, N V
AU - Sokolski Papkov, M
AU - Sandalova, T O
AU - Gubskii, I L
AU - Grinenko, N F
AU - KABANOV, A.V.
AU - Chekhonin, V. P.
PY - 2012
DA - 2012/12/02
PB - Springer Nature
SP - 274-277
IS - 2
VL - 154
PMID - 23330142
SN - 0007-4888
SN - 1573-8221
SN - 0365-9615
SN - 2413-1008
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2012_Abakumov,
author = {M A Abakumov and S A Shein and H Vishvasrao and N V Nukolova and M Sokolski Papkov and T O Sandalova and I L Gubskii and N F Grinenko and A.V. KABANOV and V. P. Chekhonin},
title = {Visualization of Experimental Glioma C6 by MRI with Magnetic Nanoparticles Conjugated with Monoclonal Antibodies to Vascular Endothelial Growth Factor},
journal = {Bulletin of Experimental Biology and Medicine},
year = {2012},
volume = {154},
publisher = {Springer Nature},
month = {dec},
url = {https://doi.org/10.1007/s10517-012-1929-8},
number = {2},
pages = {274--277},
doi = {10.1007/s10517-012-1929-8}
}
MLA
Cite this
MLA Copy
Abakumov, M. A., et al. “Visualization of Experimental Glioma C6 by MRI with Magnetic Nanoparticles Conjugated with Monoclonal Antibodies to Vascular Endothelial Growth Factor.” Bulletin of Experimental Biology and Medicine, vol. 154, no. 2, Dec. 2012, pp. 274-277. https://doi.org/10.1007/s10517-012-1929-8.