Mannich reaction in the synthesis of N,S-containing heterocycles. 14*. Unexpected formation of thiazolo[3,2-a]pyridines in the aminoalkylation of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates by isobutyraldehyde and primary amines
V V Dotsenko
1
,
S G Krivokolysko
1
1
“ChemEx Laboratory”, Vladimir Dal’ East-Ukrainian National University, Lugansk, Ukraine
|
Publication type: Journal Article
Publication date: 2012-07-01
scimago Q4
wos Q4
SJR: 0.243
CiteScore: 2.7
Impact factor: 1.0
ISSN: 00093122, 15738353
Organic Chemistry
Abstract
Treatment of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates with an excess of isobutyraldehyde and primary aromatic amines in refluxing ethanol gives the corresponding 7-aryl-3-arylamino-2,2-dimethyl-5-oxo-2,3,6,7-tetrahydro-5 H-thiazolo[3,2-a]pyridine-8-carbonitriles in 18-38 % yields.
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Total citations:
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Citations from 2024:
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(6.67%)
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Dotsenko V. V., Krivokolysko S. G. Mannich reaction in the synthesis of N,S-containing heterocycles. 14*. Unexpected formation of thiazolo[3,2-a]pyridines in the aminoalkylation of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates by isobutyraldehyde and primary amines // Chemistry of Heterocyclic Compounds. 2012. Vol. 48. No. 4. pp. 672-676.
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Dotsenko V. V., Krivokolysko S. G. Mannich reaction in the synthesis of N,S-containing heterocycles. 14*. Unexpected formation of thiazolo[3,2-a]pyridines in the aminoalkylation of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates by isobutyraldehyde and primary amines // Chemistry of Heterocyclic Compounds. 2012. Vol. 48. No. 4. pp. 672-676.
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TY - JOUR
DO - 10.1007/s10593-012-1042-y
UR - https://doi.org/10.1007/s10593-012-1042-y
TI - Mannich reaction in the synthesis of N,S-containing heterocycles. 14*. Unexpected formation of thiazolo[3,2-a]pyridines in the aminoalkylation of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates by isobutyraldehyde and primary amines
T2 - Chemistry of Heterocyclic Compounds
AU - Dotsenko, V V
AU - Krivokolysko, S G
PY - 2012
DA - 2012/07/01
PB - Springer Nature
SP - 672-676
IS - 4
VL - 48
SN - 0009-3122
SN - 1573-8353
ER -
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BibTex (up to 50 authors)
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@article{2012_Dotsenko,
author = {V V Dotsenko and S G Krivokolysko},
title = {Mannich reaction in the synthesis of N,S-containing heterocycles. 14*. Unexpected formation of thiazolo[3,2-a]pyridines in the aminoalkylation of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates by isobutyraldehyde and primary amines},
journal = {Chemistry of Heterocyclic Compounds},
year = {2012},
volume = {48},
publisher = {Springer Nature},
month = {jul},
url = {https://doi.org/10.1007/s10593-012-1042-y},
number = {4},
pages = {672--676},
doi = {10.1007/s10593-012-1042-y}
}
Cite this
MLA
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Dotsenko, V. V., and S G Krivokolysko. “Mannich reaction in the synthesis of N,S-containing heterocycles. 14*. Unexpected formation of thiazolo[3,2-a]pyridines in the aminoalkylation of N-methylmorpholinium 4-aryl-3-cyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates by isobutyraldehyde and primary amines.” Chemistry of Heterocyclic Compounds, vol. 48, no. 4, Jul. 2012, pp. 672-676. https://doi.org/10.1007/s10593-012-1042-y.
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