Condensation of 1,2-diamino-4-phenylimidazole and N-arylmaleimides with the formation of new tetrahydroimidazo[1,5-b]pyridazines
Publication type: Journal Article
Publication date: 2015-09-01
scimago Q4
wos Q4
SJR: 0.243
CiteScore: 2.7
Impact factor: 1.0
ISSN: 00093122, 15738353
Organic Chemistry
Abstract
We studied the condensation of 1,2-diamino-4-phenylimidazole with N-arylmaleimides and established that this reaction occurred upon brief refluxing of reactants in isopropanol in the presence of a catalytic amount of acetic acid and produced substituted 7-amino-N-aryl-2-oxo-5-phenyl-1,2,3,4-tetrahydroimidazo[1,5-b]pyridazine-4-carboxamides. Performing this reaction at room temperature led to the acyclic intermediates N-aryl-3-(1,2-diamino-4-phenylimidazol-5-yl)pyrrolidine-2,5-diones.
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Vandyshev D. Yu. et al. Condensation of 1,2-diamino-4-phenylimidazole and N-arylmaleimides with the formation of new tetrahydroimidazo[1,5-b]pyridazines // Chemistry of Heterocyclic Compounds. 2015. Vol. 51. No. 9. pp. 829-833.
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Vandyshev D. Yu., Shikhaliev K. S., Potapov A. Yu., Krysin M. Yu. Condensation of 1,2-diamino-4-phenylimidazole and N-arylmaleimides with the formation of new tetrahydroimidazo[1,5-b]pyridazines // Chemistry of Heterocyclic Compounds. 2015. Vol. 51. No. 9. pp. 829-833.
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TY - JOUR
DO - 10.1007/s10593-015-1782-6
UR - https://doi.org/10.1007/s10593-015-1782-6
TI - Condensation of 1,2-diamino-4-phenylimidazole and N-arylmaleimides with the formation of new tetrahydroimidazo[1,5-b]pyridazines
T2 - Chemistry of Heterocyclic Compounds
AU - Vandyshev, Dmitriy Yu
AU - Shikhaliev, Khidmet S
AU - Potapov, Andrei Yu
AU - Krysin, Mikhail Yu
PY - 2015
DA - 2015/09/01
PB - Springer Nature
SP - 829-833
IS - 9
VL - 51
SN - 0009-3122
SN - 1573-8353
ER -
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BibTex (up to 50 authors)
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@article{2015_Vandyshev,
author = {Dmitriy Yu Vandyshev and Khidmet S Shikhaliev and Andrei Yu Potapov and Mikhail Yu Krysin},
title = {Condensation of 1,2-diamino-4-phenylimidazole and N-arylmaleimides with the formation of new tetrahydroimidazo[1,5-b]pyridazines},
journal = {Chemistry of Heterocyclic Compounds},
year = {2015},
volume = {51},
publisher = {Springer Nature},
month = {sep},
url = {https://doi.org/10.1007/s10593-015-1782-6},
number = {9},
pages = {829--833},
doi = {10.1007/s10593-015-1782-6}
}
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MLA
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Vandyshev, Dmitriy Yu., et al. “Condensation of 1,2-diamino-4-phenylimidazole and N-arylmaleimides with the formation of new tetrahydroimidazo[1,5-b]pyridazines.” Chemistry of Heterocyclic Compounds, vol. 51, no. 9, Sep. 2015, pp. 829-833. https://doi.org/10.1007/s10593-015-1782-6.