Michael addition to unprotected 3-(2-nitrovinyl)indoles under the conditions of microwave synthesis
Alexander V Aksenov
1
,
Nikolai A Aksenov
1, 2
,
Anton A Skomorokhov
1
,
Inna V Aksenova
1
,
Georgii D Gryaznov
1
,
Leonid G Voskressensky
2
,
Michael A. Rubin
1, 3
Publication type: Journal Article
Publication date: 2016-11-01
scimago Q4
wos Q4
SJR: 0.243
CiteScore: 2.7
Impact factor: 1.0
ISSN: 00093122, 15738353
Organic Chemistry
Abstract
A novel highly efficient preparative method for the synthesis of substituted indoles using conjugate addition of nucleophiles to 3-(2-nitrovinyl)indoles has been developed. The addition of nucleophiles generated in the presence of a base from CH acids was investigated. The studied reactions proceed quickly and smoothly under the conditions of microwave activation and do not require protection of the indole nitrogen atom.
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Aksenov A. V. et al. Michael addition to unprotected 3-(2-nitrovinyl)indoles under the conditions of microwave synthesis // Chemistry of Heterocyclic Compounds. 2016. Vol. 52. No. 11. pp. 923-927.
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Aksenov A. V., Aksenov N. A., Skomorokhov A. A., Aksenova I. V., Gryaznov G. D., Voskressensky L. G., Rubin M. A. Michael addition to unprotected 3-(2-nitrovinyl)indoles under the conditions of microwave synthesis // Chemistry of Heterocyclic Compounds. 2016. Vol. 52. No. 11. pp. 923-927.
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RIS
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TY - JOUR
DO - 10.1007/s10593-017-1988-x
UR - https://doi.org/10.1007/s10593-017-1988-x
TI - Michael addition to unprotected 3-(2-nitrovinyl)indoles under the conditions of microwave synthesis
T2 - Chemistry of Heterocyclic Compounds
AU - Aksenov, Alexander V
AU - Aksenov, Nikolai A
AU - Skomorokhov, Anton A
AU - Aksenova, Inna V
AU - Gryaznov, Georgii D
AU - Voskressensky, Leonid G
AU - Rubin, Michael A.
PY - 2016
DA - 2016/11/01
PB - Springer Nature
SP - 923-927
IS - 11
VL - 52
SN - 0009-3122
SN - 1573-8353
ER -
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BibTex (up to 50 authors)
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@article{2016_Aksenov,
author = {Alexander V Aksenov and Nikolai A Aksenov and Anton A Skomorokhov and Inna V Aksenova and Georgii D Gryaznov and Leonid G Voskressensky and Michael A. Rubin},
title = {Michael addition to unprotected 3-(2-nitrovinyl)indoles under the conditions of microwave synthesis},
journal = {Chemistry of Heterocyclic Compounds},
year = {2016},
volume = {52},
publisher = {Springer Nature},
month = {nov},
url = {https://doi.org/10.1007/s10593-017-1988-x},
number = {11},
pages = {923--927},
doi = {10.1007/s10593-017-1988-x}
}
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MLA
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Aksenov, Alexander V., et al. “Michael addition to unprotected 3-(2-nitrovinyl)indoles under the conditions of microwave synthesis.” Chemistry of Heterocyclic Compounds, vol. 52, no. 11, Nov. 2016, pp. 923-927. https://doi.org/10.1007/s10593-017-1988-x.