Synthesis and structure of dihydroberberine nitroaryl derivatives – potential ligands for G-quadruplexes
Тип публикации: Journal Article
Дата публикации: 2017-03-01
scimago Q4
wos Q4
БС3
SJR: 0.243
CiteScore: 2.7
Impact factor: 1.0
ISSN: 00093122, 15738353
Organic Chemistry
Краткое описание
A method was developed for the synthesis of dihydroberberine nitroaryl derivatives on the basis of dihydroberberine reactions with aromatic electrophiles (picryl chloride, 4-chloro-7-nitrobenzofurazan, 4-chloro-5,7-dinitrobenzofurazan, and 7-chloro-4,6-dinitrobenzofuroxan). The obtained 13-substituted dihydroberberine derivatives represent structures with significant intramolecular charge transfer and, according to the results of molecular docking analysis, can effectively bind with G-quadruplexes of telomeric DNA fragments.
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Burov O. N. et al. Synthesis and structure of dihydroberberine nitroaryl derivatives – potential ligands for G-quadruplexes // Chemistry of Heterocyclic Compounds. 2017. Vol. 53. No. 3. pp. 335-340.
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Burov O. N., Kurbatov S. V., Kletskii M. E., Zagrebaev A. D., Mikhailov I. E. Synthesis and structure of dihydroberberine nitroaryl derivatives – potential ligands for G-quadruplexes // Chemistry of Heterocyclic Compounds. 2017. Vol. 53. No. 3. pp. 335-340.
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TY - JOUR
DO - 10.1007/s10593-017-2055-3
UR - https://doi.org/10.1007/s10593-017-2055-3
TI - Synthesis and structure of dihydroberberine nitroaryl derivatives – potential ligands for G-quadruplexes
T2 - Chemistry of Heterocyclic Compounds
AU - Burov, Oleg N
AU - Kurbatov, Sergey V.
AU - Kletskii, Mikhail E
AU - Zagrebaev, Alexander D
AU - Mikhailov, Igor E
PY - 2017
DA - 2017/03/01
PB - Springer Nature
SP - 335-340
IS - 3
VL - 53
SN - 0009-3122
SN - 1573-8353
ER -
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@article{2017_Burov,
author = {Oleg N Burov and Sergey V. Kurbatov and Mikhail E Kletskii and Alexander D Zagrebaev and Igor E Mikhailov},
title = {Synthesis and structure of dihydroberberine nitroaryl derivatives – potential ligands for G-quadruplexes},
journal = {Chemistry of Heterocyclic Compounds},
year = {2017},
volume = {53},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s10593-017-2055-3},
number = {3},
pages = {335--340},
doi = {10.1007/s10593-017-2055-3}
}
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Burov, Oleg N., et al. “Synthesis and structure of dihydroberberine nitroaryl derivatives – potential ligands for G-quadruplexes.” Chemistry of Heterocyclic Compounds, vol. 53, no. 3, Mar. 2017, pp. 335-340. https://doi.org/10.1007/s10593-017-2055-3.