Springer Nature
Chemistry of Heterocyclic Compounds
,  volume 54 ,  issue 8 ,  pages 804-811

Synthesis and structure of diamino derivatives of pyrano-[3,4-c]pyridines and 5,6,7,8-tetrahydroisoquinolines

Publication type: Journal Article
Publication date: 2018-08-01
Springer Nature
scimago Q4
wos Q4
SJR: 0.243
CiteScore: 2.7
Impact factor: 1.0
ISSN: 00093122, 15738353
Organic Chemistry
Abstract
A new and effective method was developed for obtaining diamino derivatives of pyrano[3,4-c]pyridines and 5,6,7,8-tetrahydro-isoquinolines from 3-cyanopyridin-2(1H)-ones by Smiles rearrangement of the respective oxyacetamides. The structures of the synthesized compounds were studied by NMR spectroscopy and X-ray diffraction analysis. The results of X-ray diffraction studies revealed the presence of intermolecular hydrogen bonds in 6-(benzylamino)-3,3-dimethyl-8-(pyrrolidin-1-yl)-3,4-dihydro-1H-pyrano-[3,4-c]pyridine-5-carbonitrile. The obtained compounds were also tested for antimicrobial activity.
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Paronikyan E. G. et al. Synthesis and structure of diamino derivatives of pyrano-[3,4-c]pyridines and 5,6,7,8-tetrahydroisoquinolines // Chemistry of Heterocyclic Compounds. 2018. Vol. 54. No. 8. pp. 804-811.
GOST all authors (up to 50) Copy
Paronikyan E. G., Dashyan S. S., Panosyan H. A., Ayvazyan A. G., Tamazyan R. A. Synthesis and structure of diamino derivatives of pyrano-[3,4-c]pyridines and 5,6,7,8-tetrahydroisoquinolines // Chemistry of Heterocyclic Compounds. 2018. Vol. 54. No. 8. pp. 804-811.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s10593-018-2353-4
UR - https://doi.org/10.1007/s10593-018-2353-4
TI - Synthesis and structure of diamino derivatives of pyrano-[3,4-c]pyridines and 5,6,7,8-tetrahydroisoquinolines
T2 - Chemistry of Heterocyclic Compounds
AU - Paronikyan, Ervand G
AU - Dashyan, Shushanik Sh
AU - Panosyan, Henrik A.
AU - Ayvazyan, Armen G.
AU - Tamazyan, Rafael A.
PY - 2018
DA - 2018/08/01
PB - Springer Nature
SP - 804-811
IS - 8
VL - 54
SN - 0009-3122
SN - 1573-8353
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Paronikyan,
author = {Ervand G Paronikyan and Shushanik Sh Dashyan and Henrik A. Panosyan and Armen G. Ayvazyan and Rafael A. Tamazyan},
title = {Synthesis and structure of diamino derivatives of pyrano-[3,4-c]pyridines and 5,6,7,8-tetrahydroisoquinolines},
journal = {Chemistry of Heterocyclic Compounds},
year = {2018},
volume = {54},
publisher = {Springer Nature},
month = {aug},
url = {https://doi.org/10.1007/s10593-018-2353-4},
number = {8},
pages = {804--811},
doi = {10.1007/s10593-018-2353-4}
}
MLA
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MLA Copy
Paronikyan, Ervand G., et al. “Synthesis and structure of diamino derivatives of pyrano-[3,4-c]pyridines and 5,6,7,8-tetrahydroisoquinolines.” Chemistry of Heterocyclic Compounds, vol. 54, no. 8, Aug. 2018, pp. 804-811. https://doi.org/10.1007/s10593-018-2353-4.