Synthesis and specific nootropic activity of (–)-cytisine derivatives with carbamide and thiocarbamide moieties in their structure
Publication type: Journal Article
Publication date: 2012-09-07
scimago Q3
wos Q4
SJR: 0.296
CiteScore: 1.3
Impact factor: 0.9
ISSN: 00093130, 15738388
General Chemistry
General Biochemistry, Genetics and Molecular Biology
Plant Science
Abstract
N-(methylcytisinyl)-N′-substituted ureas, N-substituted cytisine-12-carbamides, and cytisine-12-thiocarbamide were prepared by reaction of (–)-cytisine with urea and thiourea and of (–)-cytisine and its 12-N-methyl-3-amino derivative with isocyanates. Their specific nootropic activity was studied in vivo. The therapeutic index was determined for the lead compound. Promising candidates for further pharmacological testing were found.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
2
4
6
8
10
|
|
|
Chemistry of Natural Compounds
10 publications, 31.25%
|
|
|
Natural Product Research
4 publications, 12.5%
|
|
|
Pharmaceutical Chemistry Journal
2 publications, 6.25%
|
|
|
Journal of Agricultural and Food Chemistry
2 publications, 6.25%
|
|
|
Mini-Reviews in Medicinal Chemistry
1 publication, 3.13%
|
|
|
Chemical Papers
1 publication, 3.13%
|
|
|
European Journal of Medicinal Chemistry
1 publication, 3.13%
|
|
|
Tetrahedron Asymmetry
1 publication, 3.13%
|
|
|
Toxicology Reports
1 publication, 3.13%
|
|
|
Tetrahedron
1 publication, 3.13%
|
|
|
Journal of Photochemistry and Photobiology A: Chemistry
1 publication, 3.13%
|
|
|
Chemical Reviews
1 publication, 3.13%
|
|
|
Journal of Materials Chemistry A
1 publication, 3.13%
|
|
|
Russian Journal of Bioorganic Chemistry
1 publication, 3.13%
|
|
|
Journal of Structural Chemistry
1 publication, 3.13%
|
|
|
Russian Chemical Bulletin
1 publication, 3.13%
|
|
|
Mendeleev Communications
1 publication, 3.13%
|
|
|
Журнал Общей Химии
1 publication, 3.13%
|
|
|
2
4
6
8
10
|
Publishers
|
2
4
6
8
10
12
14
|
|
|
Springer Nature
14 publications, 43.75%
|
|
|
Elsevier
5 publications, 15.63%
|
|
|
Taylor & Francis
4 publications, 12.5%
|
|
|
American Chemical Society (ACS)
3 publications, 9.38%
|
|
|
Pleiades Publishing
2 publications, 6.25%
|
|
|
Bentham Science Publishers Ltd.
1 publication, 3.13%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 3.13%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 3.13%
|
|
|
The Russian Academy of Sciences
1 publication, 3.13%
|
|
|
2
4
6
8
10
12
14
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
32
Total citations:
32
Citations from 2025:
1
(3.13%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Tsypysheva I. P. et al. Synthesis and specific nootropic activity of (–)-cytisine derivatives with carbamide and thiocarbamide moieties in their structure // Chemistry of Natural Compounds. 2012. Vol. 48. No. 4. pp. 629-634.
GOST all authors (up to 50)
Copy
Tsypysheva I. P., Kovalskaya A. V., Makara N. S., Lobov A. N., Petrenko I. A., Galkin E. G., Sapozhnikova T. A., Zarudii F. S., Yunusov M. S. Synthesis and specific nootropic activity of (–)-cytisine derivatives with carbamide and thiocarbamide moieties in their structure // Chemistry of Natural Compounds. 2012. Vol. 48. No. 4. pp. 629-634.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s10600-012-0329-7
UR - https://doi.org/10.1007/s10600-012-0329-7
TI - Synthesis and specific nootropic activity of (–)-cytisine derivatives with carbamide and thiocarbamide moieties in their structure
T2 - Chemistry of Natural Compounds
AU - Tsypysheva, I P
AU - Kovalskaya, A V
AU - Makara, N S
AU - Lobov, A N
AU - Petrenko, I A
AU - Galkin, E G
AU - Sapozhnikova, T A
AU - Zarudii, F S
AU - Yunusov, M. S.
PY - 2012
DA - 2012/09/07
PB - Springer Nature
SP - 629-634
IS - 4
VL - 48
SN - 0009-3130
SN - 1573-8388
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2012_Tsypysheva,
author = {I P Tsypysheva and A V Kovalskaya and N S Makara and A N Lobov and I A Petrenko and E G Galkin and T A Sapozhnikova and F S Zarudii and M. S. Yunusov},
title = {Synthesis and specific nootropic activity of (–)-cytisine derivatives with carbamide and thiocarbamide moieties in their structure},
journal = {Chemistry of Natural Compounds},
year = {2012},
volume = {48},
publisher = {Springer Nature},
month = {sep},
url = {https://doi.org/10.1007/s10600-012-0329-7},
number = {4},
pages = {629--634},
doi = {10.1007/s10600-012-0329-7}
}
Cite this
MLA
Copy
Tsypysheva, I. P., et al. “Synthesis and specific nootropic activity of (–)-cytisine derivatives with carbamide and thiocarbamide moieties in their structure.” Chemistry of Natural Compounds, vol. 48, no. 4, Sep. 2012, pp. 629-634. https://doi.org/10.1007/s10600-012-0329-7.