volume 75 issue 9-10 pages 377-382

Nanoporous Glass with Controlled Pore Size for High-Efficiency Synthesis of Oligonucleotides

K I Piyanzina 1
A A Stepko 1
A N Natyrov 2
A. M. Mikhailov 1
V I Savinkov 1
V. N. Sigaev 1
Publication typeJournal Article
Publication date2019-01-25
scimago Q3
wos Q4
SJR0.234
CiteScore1.0
Impact factor0.6
ISSN03617610, 15738515
Materials Chemistry
Ceramics and Composites
Mechanics of Materials
Abstract
The results of work on the development of powder nanoporous glass (NPG) with controlled pore size for solid-phase synthesis of oligonucleotides with heightened product yield are presented. NPG with a narrow pore-size distribution was obtained by varying the parameters of the heat and chemical treatment of sodium-borosilicate glasses. It was found that the functional charge of the material is equal to 72 μmol/g. It is shown that using the developed NPG in the synthesis of long-chain oligonucleotides increases the product yield more than seven-fold compared with the analogous material offered on the market.
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Shakhgildyan G. Yu. et al. Nanoporous Glass with Controlled Pore Size for High-Efficiency Synthesis of Oligonucleotides // Glass and Ceramics (English translation of Steklo i Keramika). 2019. Vol. 75. No. 9-10. pp. 377-382.
GOST all authors (up to 50) Copy
Shakhgildyan G. Yu., Piyanzina K. I., Stepko A. A., Natyrov A. N., Mikhailov A. M., Savinkov V. I., Sigaev V. N. Nanoporous Glass with Controlled Pore Size for High-Efficiency Synthesis of Oligonucleotides // Glass and Ceramics (English translation of Steklo i Keramika). 2019. Vol. 75. No. 9-10. pp. 377-382.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s10717-019-00089-3
UR - https://doi.org/10.1007/s10717-019-00089-3
TI - Nanoporous Glass with Controlled Pore Size for High-Efficiency Synthesis of Oligonucleotides
T2 - Glass and Ceramics (English translation of Steklo i Keramika)
AU - Shakhgildyan, G Yu
AU - Piyanzina, K I
AU - Stepko, A A
AU - Natyrov, A N
AU - Mikhailov, A. M.
AU - Savinkov, V I
AU - Sigaev, V. N.
PY - 2019
DA - 2019/01/25
PB - Springer Nature
SP - 377-382
IS - 9-10
VL - 75
SN - 0361-7610
SN - 1573-8515
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Shakhgildyan,
author = {G Yu Shakhgildyan and K I Piyanzina and A A Stepko and A N Natyrov and A. M. Mikhailov and V I Savinkov and V. N. Sigaev},
title = {Nanoporous Glass with Controlled Pore Size for High-Efficiency Synthesis of Oligonucleotides},
journal = {Glass and Ceramics (English translation of Steklo i Keramika)},
year = {2019},
volume = {75},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s10717-019-00089-3},
number = {9-10},
pages = {377--382},
doi = {10.1007/s10717-019-00089-3}
}
MLA
Cite this
MLA Copy
Shakhgildyan, G. Yu., et al. “Nanoporous Glass with Controlled Pore Size for High-Efficiency Synthesis of Oligonucleotides.” Glass and Ceramics (English translation of Steklo i Keramika), vol. 75, no. 9-10, Jan. 2019, pp. 377-382. https://doi.org/10.1007/s10717-019-00089-3.