Journal of Fluorescence, volume 22, issue 1, pages 193-199

Microwave-Assisted Aqueous Synthesis of Highly Luminescent Carboxymethyl Chitosan-Coated CdTe/CdS Quantum Dots as Fluorescent Probe for Live Cell Imaging

Zhenyu He 1, 2
Honghao Zhu 2
Peijiang Zhou 1
Publication typeJournal Article
Publication date2011-08-20
Quartile SCImago
Q1
Quartile WOS
Q3
Impact factor2.7
ISSN10530509, 15734994
Biochemistry
Spectroscopy
Clinical Biochemistry
Law
Sociology and Political Science
Social Sciences (miscellaneous)
Clinical Psychology
Abstract
This paper describes the development of a simplified and rapid method for the aqueous synthesis of quantum dots (QDs) with CdTe cores and gradient CdS external shells (CdTe/CdS QDs) aided by microwave irradiation. Several synthesis parameters, such as molar ratio of reagents, pH, reaction temperature, and reaction time, were studied in details. Under the optimized conditions, highly effective CdTe/CdS QDs could be synthesized in aqueous phase in only 15 min. In order to improve the biocompatibility of the CdTe/CdS QDs, these QDs were then interacted with carboxymethyl chitosan (CMC) so as they could be used as fluorescent probes in the aqueous phase. With the incorporation of CMC, the stability of modified QDs was found to have improved significantly (from 4 months to more than 10 months at room temperature). The photoluminescence quantum yield (PLQY) of the modified QDs could reach 75%, other parameters include a full width at half maximum of the emission (FWHM) spectrum as 40 ~ 60 nm, and an average size, estimated from electron microscopic images, as 3.5 nm. As fluorescent probes, these modified QDs were successfully used for imaging live Madin–Darby canine kidney (MDCK) cells, in which the preliminary results indicated that these modified QDs demonstrated good biocompatibility and showed promising applications for bio-labeling and imaging.

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GOST Copy
He Z. et al. Microwave-Assisted Aqueous Synthesis of Highly Luminescent Carboxymethyl Chitosan-Coated CdTe/CdS Quantum Dots as Fluorescent Probe for Live Cell Imaging // Journal of Fluorescence. 2011. Vol. 22. No. 1. pp. 193-199.
GOST all authors (up to 50) Copy
He Z., Zhu H., Zhou P. Microwave-Assisted Aqueous Synthesis of Highly Luminescent Carboxymethyl Chitosan-Coated CdTe/CdS Quantum Dots as Fluorescent Probe for Live Cell Imaging // Journal of Fluorescence. 2011. Vol. 22. No. 1. pp. 193-199.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1007/s10895-011-0946-8
UR - https://doi.org/10.1007/s10895-011-0946-8
TI - Microwave-Assisted Aqueous Synthesis of Highly Luminescent Carboxymethyl Chitosan-Coated CdTe/CdS Quantum Dots as Fluorescent Probe for Live Cell Imaging
T2 - Journal of Fluorescence
AU - He, Zhenyu
AU - Zhu, Honghao
AU - Zhou, Peijiang
PY - 2011
DA - 2011/08/20 00:00:00
PB - Springer Nature
SP - 193-199
IS - 1
VL - 22
SN - 1053-0509
SN - 1573-4994
ER -
BibTex |
Cite this
BibTex Copy
@article{2011_He,
author = {Zhenyu He and Honghao Zhu and Peijiang Zhou},
title = {Microwave-Assisted Aqueous Synthesis of Highly Luminescent Carboxymethyl Chitosan-Coated CdTe/CdS Quantum Dots as Fluorescent Probe for Live Cell Imaging},
journal = {Journal of Fluorescence},
year = {2011},
volume = {22},
publisher = {Springer Nature},
month = {aug},
url = {https://doi.org/10.1007/s10895-011-0946-8},
number = {1},
pages = {193--199},
doi = {10.1007/s10895-011-0946-8}
}
MLA
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MLA Copy
He, Zhenyu, et al. “Microwave-Assisted Aqueous Synthesis of Highly Luminescent Carboxymethyl Chitosan-Coated CdTe/CdS Quantum Dots as Fluorescent Probe for Live Cell Imaging.” Journal of Fluorescence, vol. 22, no. 1, Aug. 2011, pp. 193-199. https://doi.org/10.1007/s10895-011-0946-8.
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