Electrospun Methacrylate-Based Copolymer/Indomethacin Fibers and Their Release Characteristics of Indomethacin
Тип публикации: Journal Article
Дата публикации: 2006-09-28
scimago Q2
wos Q3
БС2
SJR: 0.505
CiteScore: 5.1
Impact factor: 2.8
ISSN: 10229760, 15728935
Materials Chemistry
Organic Chemistry
Polymers and Plastics
Краткое описание
Three methacrylate-based copolymers [i.e., poly(methacrylic acid-co-methyl methacrylate) (E-L100), poly(ethyl acrylate-co-methyl methacrylate-co-trimethyl-ammonioethyl methacrylate chloride) (E-RLPO), and poly(butyl methacrylate-co-(2-dimethylaminoethyl) methacrylate-co-methyl methacrylate) (E-EPO)] were successfully electrospun into fibers, using ethanol (EtOH) as the spinning solvent. However, electrospinning of these methacrylate-based copolymers and indomethacin (10% by weight of the copolymer) was only successful when an equivolume of EtOH and ethylacetate (EA) was used as the co-solvent system. The drug-loaded as-spun copolymeric fibers appeared to be flat, with the size ranging between 1.2 and 2.5 μm. At 24 h, the amount of the drug released from these drug-loaded as-spun copolymer fibers was about 55%, 30%, and 18% for drug-loaded as-spun E-EPO, E-L100, and E-RLPO fibers, respectively.
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ГОСТ
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Pornsopone V. et al. Electrospun Methacrylate-Based Copolymer/Indomethacin Fibers and Their Release Characteristics of Indomethacin // Journal of Polymer Research. 2006. Vol. 14. No. 1. pp. 53-59.
ГОСТ со всеми авторами (до 50)
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Pornsopone V., Supaphol P., Rangkupan R., Tantayanon S. Electrospun Methacrylate-Based Copolymer/Indomethacin Fibers and Their Release Characteristics of Indomethacin // Journal of Polymer Research. 2006. Vol. 14. No. 1. pp. 53-59.
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TY - JOUR
DO - 10.1007/s10965-006-9080-8
UR - https://doi.org/10.1007/s10965-006-9080-8
TI - Electrospun Methacrylate-Based Copolymer/Indomethacin Fibers and Their Release Characteristics of Indomethacin
T2 - Journal of Polymer Research
AU - Pornsopone, Varaporn
AU - Supaphol, Pitt
AU - Rangkupan, Ratthapol
AU - Tantayanon, Supawan
PY - 2006
DA - 2006/09/28
PB - Springer Nature
SP - 53-59
IS - 1
VL - 14
SN - 1022-9760
SN - 1572-8935
ER -
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BibTex (до 50 авторов)
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@article{2006_Pornsopone,
author = {Varaporn Pornsopone and Pitt Supaphol and Ratthapol Rangkupan and Supawan Tantayanon},
title = {Electrospun Methacrylate-Based Copolymer/Indomethacin Fibers and Their Release Characteristics of Indomethacin},
journal = {Journal of Polymer Research},
year = {2006},
volume = {14},
publisher = {Springer Nature},
month = {sep},
url = {https://doi.org/10.1007/s10965-006-9080-8},
number = {1},
pages = {53--59},
doi = {10.1007/s10965-006-9080-8}
}
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MLA
Скопировать
Pornsopone, Varaporn, et al. “Electrospun Methacrylate-Based Copolymer/Indomethacin Fibers and Their Release Characteristics of Indomethacin.” Journal of Polymer Research, vol. 14, no. 1, Sep. 2006, pp. 53-59. https://doi.org/10.1007/s10965-006-9080-8.