Synthesis of benzimidazole[2.1-b][1,3]oxazine spirooxindoles via three-component reaction of N-benzylbenzimidazole, acetylenedicarboxylates, and N-alkylisatins
Publication type: Journal Article
Publication date: 2014-08-19
scimago Q2
wos Q2
SJR: 0.646
CiteScore: 8.5
Impact factor: 3.8
ISSN: 13811991, 1573501X
PubMed ID:
25135055
Catalysis
Organic Chemistry
Drug Discovery
Inorganic Chemistry
Physical and Theoretical Chemistry
Molecular Biology
General Medicine
Information Systems
Abstract
The three-component reaction of $$N$$ -benzylbenzimidazole, dialkyl acetylenedicarboxylate, and $$N$$ -alkylisatins in tetrahydrofuran at room temperature afforded the novel functionalized benzimidazole[2.1-b][1,3]oxazine spirooxindoles in good yields. $${}^{1}$$ H NMR spectra indicated that two diastereoisomers with a ratio of 1:3–1:6 exist in the obtained spirooxindole derivatives. .
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Total citations:
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Citations from 2024:
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(14.29%)
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Zhang L. J., Yan C. Synthesis of benzimidazole[2.1-b][1,3]oxazine spirooxindoles via three-component reaction of N-benzylbenzimidazole, acetylenedicarboxylates, and N-alkylisatins // Molecular Diversity. 2014. Vol. 18. No. 4. pp. 787-796.
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Zhang L. J., Yan C. Synthesis of benzimidazole[2.1-b][1,3]oxazine spirooxindoles via three-component reaction of N-benzylbenzimidazole, acetylenedicarboxylates, and N-alkylisatins // Molecular Diversity. 2014. Vol. 18. No. 4. pp. 787-796.
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TY - JOUR
DO - 10.1007/s11030-014-9538-2
UR - https://doi.org/10.1007/s11030-014-9538-2
TI - Synthesis of benzimidazole[2.1-b][1,3]oxazine spirooxindoles via three-component reaction of N-benzylbenzimidazole, acetylenedicarboxylates, and N-alkylisatins
T2 - Molecular Diversity
AU - Zhang, Li Juan
AU - Yan, Chao-Guo
PY - 2014
DA - 2014/08/19
PB - Springer Nature
SP - 787-796
IS - 4
VL - 18
PMID - 25135055
SN - 1381-1991
SN - 1573-501X
ER -
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BibTex (up to 50 authors)
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@article{2014_Zhang,
author = {Li Juan Zhang and Chao-Guo Yan},
title = {Synthesis of benzimidazole[2.1-b][1,3]oxazine spirooxindoles via three-component reaction of N-benzylbenzimidazole, acetylenedicarboxylates, and N-alkylisatins},
journal = {Molecular Diversity},
year = {2014},
volume = {18},
publisher = {Springer Nature},
month = {aug},
url = {https://doi.org/10.1007/s11030-014-9538-2},
number = {4},
pages = {787--796},
doi = {10.1007/s11030-014-9538-2}
}
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MLA
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Zhang, Li Juan, and Chao-Guo Yan. “Synthesis of benzimidazole[2.1-b][1,3]oxazine spirooxindoles via three-component reaction of N-benzylbenzimidazole, acetylenedicarboxylates, and N-alkylisatins.” Molecular Diversity, vol. 18, no. 4, Aug. 2014, pp. 787-796. https://doi.org/10.1007/s11030-014-9538-2.