Gold nanorod stabilized by thiolated chitosan as photothermal absorber for cancer cell treatment
Publication type: Journal Article
Publication date: 2010-12-18
scimago Q2
wos Q2
SJR: 0.469
CiteScore: 4.0
Impact factor: 2.6
ISSN: 13880764, 1572896X
General Chemistry
Atomic and Molecular Physics, and Optics
Condensed Matter Physics
General Materials Science
Bioengineering
Modeling and Simulation
Abstract
Gold nanorod (GNR) has great potential in the field of cancer therapy because of its photophysical property in converting near-infrared (NIR) laser light into heat. Fabrication of GNRs by seed-mediated growth method with the aid of cetyltrimethylammonium bromide (CTAB) is a popular approach. However, due to high cytotoxicity of CTAB, it is necessary to modify the surface of CTAB-passivated GNRs for cell-related studies. In this study, thiolated chitosan was synthesized and harnessed to replace CTAB originally used to stabilize GNRs. The average size and morphological shape of CTAB-passivated GNRs (66.0 nm) and thiolated chitosan-modified GNRs (CGNRs) (84.9 nm) were determined by dynamic light scattering and transmission electron microscopy. X-ray photoelectron spectroscopy was used to confirm the existence of Au–S binding energy at 162.4 eV. Cytotoxicity study revealed that CGNRs were much biocompatible than CTAB-stabilized GNRs. Our results showed that CGNRs functionalized with folic acid (FA) could be internalized by human colon HT-29 cancer cells via folate-mediated endocytosis. From the viability of CGNR-laden HT-29 cells irradiated with 808-nm NIR laser light, we demonstrated that CGNR is a potential photothermal nano-absorber for the ablation of malignant cells under NIR laser exposure.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
Journal of Nanoparticle Research
4 publications, 7.41%
|
|
|
Scientific Reports
3 publications, 5.56%
|
|
|
International Journal of Biological Macromolecules
3 publications, 5.56%
|
|
|
Journal of Materials Chemistry B
3 publications, 5.56%
|
|
|
Nanotechnology
2 publications, 3.7%
|
|
|
Carbohydrate Polymers
2 publications, 3.7%
|
|
|
Current Drug Metabolism
1 publication, 1.85%
|
|
|
Nanomedicine
1 publication, 1.85%
|
|
|
Nanomaterials and Nanotechnology
1 publication, 1.85%
|
|
|
International Journal of Molecular Sciences
1 publication, 1.85%
|
|
|
Gold Bulletin
1 publication, 1.85%
|
|
|
Chinese Science Bulletin
1 publication, 1.85%
|
|
|
Journal of Colloid and Interface Science
1 publication, 1.85%
|
|
|
Acta Biomaterialia
1 publication, 1.85%
|
|
|
Journal of Controlled Release
1 publication, 1.85%
|
|
|
Applied Surface Science
1 publication, 1.85%
|
|
|
Materials Science and Engineering C
1 publication, 1.85%
|
|
|
Coordination Chemistry Reviews
1 publication, 1.85%
|
|
|
Biosensors and Bioelectronics
1 publication, 1.85%
|
|
|
Advanced NanoBiomed Research
1 publication, 1.85%
|
|
|
Advanced Materials
1 publication, 1.85%
|
|
|
Macromolecular Rapid Communications
1 publication, 1.85%
|
|
|
ChemPlusChem
1 publication, 1.85%
|
|
|
Chemistry of Materials
1 publication, 1.85%
|
|
|
ACS applied materials & interfaces
1 publication, 1.85%
|
|
|
ACS Applied Bio Materials
1 publication, 1.85%
|
|
|
Dalton Transactions
1 publication, 1.85%
|
|
|
Analytical Methods
1 publication, 1.85%
|
|
|
Chemical Communications
1 publication, 1.85%
|
|
|
1
2
3
4
|
Publishers
|
2
4
6
8
10
12
14
|
|
|
Elsevier
13 publications, 24.07%
|
|
|
Springer Nature
10 publications, 18.52%
|
|
|
Royal Society of Chemistry (RSC)
8 publications, 14.81%
|
|
|
Wiley
5 publications, 9.26%
|
|
|
American Chemical Society (ACS)
3 publications, 5.56%
|
|
|
Taylor & Francis
2 publications, 3.7%
|
|
|
IOP Publishing
2 publications, 3.7%
|
|
|
Bentham Science Publishers Ltd.
1 publication, 1.85%
|
|
|
SAGE
1 publication, 1.85%
|
|
|
MDPI
1 publication, 1.85%
|
|
|
Institute of Electrical and Electronics Engineers (IEEE)
1 publication, 1.85%
|
|
|
Walter de Gruyter
1 publication, 1.85%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 1.85%
|
|
|
2
4
6
8
10
12
14
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
54
Total citations:
54
Citations from 2024:
4
(7.4%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Wang C., Chang C., Peng C. Gold nanorod stabilized by thiolated chitosan as photothermal absorber for cancer cell treatment // Journal of Nanoparticle Research. 2010. Vol. 13. No. 7. pp. 2749-2758.
GOST all authors (up to 50)
Copy
Wang C., Chang C., Peng C. Gold nanorod stabilized by thiolated chitosan as photothermal absorber for cancer cell treatment // Journal of Nanoparticle Research. 2010. Vol. 13. No. 7. pp. 2749-2758.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s11051-010-0162-5
UR - https://doi.org/10.1007/s11051-010-0162-5
TI - Gold nanorod stabilized by thiolated chitosan as photothermal absorber for cancer cell treatment
T2 - Journal of Nanoparticle Research
AU - Wang, Chung-Hao
AU - Chang, Chia-Wei
AU - Peng, Ching-An
PY - 2010
DA - 2010/12/18
PB - Springer Nature
SP - 2749-2758
IS - 7
VL - 13
SN - 1388-0764
SN - 1572-896X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2010_Wang,
author = {Chung-Hao Wang and Chia-Wei Chang and Ching-An Peng},
title = {Gold nanorod stabilized by thiolated chitosan as photothermal absorber for cancer cell treatment},
journal = {Journal of Nanoparticle Research},
year = {2010},
volume = {13},
publisher = {Springer Nature},
month = {dec},
url = {https://doi.org/10.1007/s11051-010-0162-5},
number = {7},
pages = {2749--2758},
doi = {10.1007/s11051-010-0162-5}
}
Cite this
MLA
Copy
Wang, Chung-Hao, et al. “Gold nanorod stabilized by thiolated chitosan as photothermal absorber for cancer cell treatment.” Journal of Nanoparticle Research, vol. 13, no. 7, Dec. 2010, pp. 2749-2758. https://doi.org/10.1007/s11051-010-0162-5.