Springer Nature
Pharmaceutical Chemistry Journal
,  volume 45 ,  issue 9 ,  pages 522-525

Synthesis and cytotoxic activity of azidonaphthazarins

Publication type: Journal Article
Publication date: 2011-12-13
Springer Nature
scimago Q4
wos Q4
SJR: 0.219
CiteScore: 1.4
Impact factor: 1.0
ISSN: 0091150X, 15739031
Drug Discovery
Pharmacology
Abstract
Preparative methods have been developed for the synthesis of azidonaphthazarins. It is established that 2-hydroxy- and 2-alkoxy-6,7-dichloronaphthazarins react regiospecifically with sodium azide in MeOH to yield the corresponding 6-azido derivatives. The cytotoxic activity and contraceptive properties of the synthesized azidonaphthazarins have been investigated using the sperm and eggs of the sea urchin Strongylocentrotus intermedius.
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GOST |
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GOST Copy
Pokhilo N. D., Kiseleva M. I., Anufriev V. F. Synthesis and cytotoxic activity of azidonaphthazarins // Pharmaceutical Chemistry Journal. 2011. Vol. 45. No. 9. pp. 522-525.
GOST all authors (up to 50) Copy
Pokhilo N. D., Kiseleva M. I., Anufriev V. F. Synthesis and cytotoxic activity of azidonaphthazarins // Pharmaceutical Chemistry Journal. 2011. Vol. 45. No. 9. pp. 522-525.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1007/s11094-011-0671-2
UR - https://doi.org/10.1007/s11094-011-0671-2
TI - Synthesis and cytotoxic activity of azidonaphthazarins
T2 - Pharmaceutical Chemistry Journal
AU - Pokhilo, N. D.
AU - Kiseleva, M. I.
AU - Anufriev, V. F.
PY - 2011
DA - 2011/12/13
PB - Springer Nature
SP - 522-525
IS - 9
VL - 45
SN - 0091-150X
SN - 1573-9031
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2011_Pokhilo,
author = {N. D. Pokhilo and M. I. Kiseleva and V. F. Anufriev},
title = {Synthesis and cytotoxic activity of azidonaphthazarins},
journal = {Pharmaceutical Chemistry Journal},
year = {2011},
volume = {45},
publisher = {Springer Nature},
month = {dec},
url = {https://doi.org/10.1007/s11094-011-0671-2},
number = {9},
pages = {522--525},
doi = {10.1007/s11094-011-0671-2}
}
MLA
Cite this
MLA Copy
Pokhilo, N. D., et al. “Synthesis and cytotoxic activity of azidonaphthazarins.” Pharmaceutical Chemistry Journal, vol. 45, no. 9, Dec. 2011, pp. 522-525. https://doi.org/10.1007/s11094-011-0671-2.