Synthesis, Antimicrobial Properties, and Toxicity of a Nanobiocomposite Based on Ag(0) Particles and Poly(1-Vinyl-1,2,4-Triazole)
L M Sosedova
1
,
M. A. Novikov
1
,
E A Titov
1
,
A S Pozdnyakov
2
,
S. A. Korzhova
2
,
T G Ermakova
2
,
G F Prozorova
2
1
East-Siberian Medico-Ecological Research Institute, Angarsk, Russia
|
Publication type: Journal Article
Publication date: 2019-02-09
scimago Q4
wos Q4
SJR: 0.219
CiteScore: 1.4
Impact factor: 1.0
ISSN: 0091150X, 15739031
Drug Discovery
Pharmacology
Abstract
The synthesis of a water-soluble polymer nanocomposite with Ag(0) particles encapsulated in a poly(1-vinyl-1,2,4-triazole) matrix is reported. The nanocomposite contains isolated spherical Ag(0) particles sized from 2 to 8 nm that are uniformly distributed in the polymer matrix and have a characteristic plasmonic absorption maximum at 412 nm. The new nanocomposite belongs to marginally hazardous category 4. The structural morphology of animal brain tissue is not disturbed after subacute intragastric injection. The bacteriostatic concentration of the nanocomposite varies in the range 0.5 – 32 μg/mL; bactericidal, 1 – 64 μg/mL.
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Sosedova L. M. et al. Synthesis, Antimicrobial Properties, and Toxicity of a Nanobiocomposite Based on Ag(0) Particles and Poly(1-Vinyl-1,2,4-Triazole) // Pharmaceutical Chemistry Journal. 2019. Vol. 52. No. 11. pp. 912-916.
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Sosedova L. M., Novikov M. A., Titov E. A., Pozdnyakov A. S., Korzhova S. A., Ermakova T. G., Prozorova G. F. Synthesis, Antimicrobial Properties, and Toxicity of a Nanobiocomposite Based on Ag(0) Particles and Poly(1-Vinyl-1,2,4-Triazole) // Pharmaceutical Chemistry Journal. 2019. Vol. 52. No. 11. pp. 912-916.
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RIS
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TY - JOUR
DO - 10.1007/s11094-019-01925-0
UR - https://doi.org/10.1007/s11094-019-01925-0
TI - Synthesis, Antimicrobial Properties, and Toxicity of a Nanobiocomposite Based on Ag(0) Particles and Poly(1-Vinyl-1,2,4-Triazole)
T2 - Pharmaceutical Chemistry Journal
AU - Sosedova, L M
AU - Novikov, M. A.
AU - Titov, E A
AU - Pozdnyakov, A S
AU - Korzhova, S. A.
AU - Ermakova, T G
AU - Prozorova, G F
PY - 2019
DA - 2019/02/09
PB - Springer Nature
SP - 912-916
IS - 11
VL - 52
SN - 0091-150X
SN - 1573-9031
ER -
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BibTex (up to 50 authors)
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@article{2019_Sosedova,
author = {L M Sosedova and M. A. Novikov and E A Titov and A S Pozdnyakov and S. A. Korzhova and T G Ermakova and G F Prozorova},
title = {Synthesis, Antimicrobial Properties, and Toxicity of a Nanobiocomposite Based on Ag(0) Particles and Poly(1-Vinyl-1,2,4-Triazole)},
journal = {Pharmaceutical Chemistry Journal},
year = {2019},
volume = {52},
publisher = {Springer Nature},
month = {feb},
url = {https://doi.org/10.1007/s11094-019-01925-0},
number = {11},
pages = {912--916},
doi = {10.1007/s11094-019-01925-0}
}
Cite this
MLA
Copy
Sosedova, L. M., et al. “Synthesis, Antimicrobial Properties, and Toxicity of a Nanobiocomposite Based on Ag(0) Particles and Poly(1-Vinyl-1,2,4-Triazole).” Pharmaceutical Chemistry Journal, vol. 52, no. 11, Feb. 2019, pp. 912-916. https://doi.org/10.1007/s11094-019-01925-0.
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