Aluminized polyborate-catalysed green and efficient synthesis of polyhydroquinolines under solvent-free conditions

The present work reports a catalytic application of aluminized polyborate for the solvent-free one pot four-component green, efficient and cost-effective synthesis of polydroquinoline derivatives. The aluminized polyborate was synthesized from readily available non-toxic, inexpensive boric acid and aluminium trichloride and characterized by IR, XRD, SEM and EDAX techniques. The polyhydroquinolines were successfully synthesized by well-known Hantzsch condensation reaction of differently substituted aldehydes, dimedone, ethylacetoacetate and NH4OAc at 100 °C under solvent-free condition. The catalyst is stable and easy to use with some significant features such as good acidic catalytic activity, inexpensive and eco-friendly nature. Along with this, excellent product yields, short reaction time, clean reaction, operational simplicity, solvent-free condition and non-column purification are some more additional aspects of this protocol.