Catalyst-free amination of 2-fluoropyridine and 2-fluoro-5-halopyridines with adamantane amines
A S Abel
1
,
O K Grigorova
1
,
A D Averin
1
,
O A Maloshitskaya
1
,
O.A. POPOV
2
,
G M Butov
2
,
E N Savelyev
3
,
B S Orlinson
3
,
I A Novakov
3
,
2
Volzhskii Polytechnic Institute, Branch of Volgorgad State Technical University, Volzhskii, Volgograd Region, Russian Federation
|
Publication type: Journal Article
Publication date: 2015-03-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
Catalyst-free reactions of 2-fluoropyridine with amines and diamines bearing the adamantyl moiety at either the N atom or in the side chain were studied. Amines, which do not contain secondary alkyl substituents at the amino group, react with an excess of 2-fluoropyridine to give N-(pyridin-2-yl) derivatives in the yields from moderate to good. 2-Fluoro-5-halopyridines were found to be more reactive than 2-fluoropyridine.
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Abel A. S. et al. Catalyst-free amination of 2-fluoropyridine and 2-fluoro-5-halopyridines with adamantane amines // Russian Chemical Bulletin. 2015. Vol. 64. No. 3. pp. 683-688.
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Abel A. S., Grigorova O. K., Averin A. D., Maloshitskaya O. A., POPOV O., Butov G. M., Savelyev E. N., Orlinson B. S., Novakov I. A., Beletskaya I. P. Catalyst-free amination of 2-fluoropyridine and 2-fluoro-5-halopyridines with adamantane amines // Russian Chemical Bulletin. 2015. Vol. 64. No. 3. pp. 683-688.
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TY - JOUR
DO - 10.1007/s11172-015-0919-1
UR - https://doi.org/10.1007/s11172-015-0919-1
TI - Catalyst-free amination of 2-fluoropyridine and 2-fluoro-5-halopyridines with adamantane amines
T2 - Russian Chemical Bulletin
AU - Abel, A S
AU - Grigorova, O K
AU - Averin, A D
AU - Maloshitskaya, O A
AU - POPOV, O.A.
AU - Butov, G M
AU - Savelyev, E N
AU - Orlinson, B S
AU - Novakov, I A
AU - Beletskaya, I P
PY - 2015
DA - 2015/03/01
PB - Springer Nature
SP - 683-688
IS - 3
VL - 64
SN - 1066-5285
SN - 1573-9171
ER -
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@article{2015_Abel,
author = {A S Abel and O K Grigorova and A D Averin and O A Maloshitskaya and O.A. POPOV and G M Butov and E N Savelyev and B S Orlinson and I A Novakov and I P Beletskaya},
title = {Catalyst-free amination of 2-fluoropyridine and 2-fluoro-5-halopyridines with adamantane amines},
journal = {Russian Chemical Bulletin},
year = {2015},
volume = {64},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s11172-015-0919-1},
number = {3},
pages = {683--688},
doi = {10.1007/s11172-015-0919-1}
}
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MLA
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Abel, A. S., et al. “Catalyst-free amination of 2-fluoropyridine and 2-fluoro-5-halopyridines with adamantane amines.” Russian Chemical Bulletin, vol. 64, no. 3, Mar. 2015, pp. 683-688. https://doi.org/10.1007/s11172-015-0919-1.
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