Springer Nature
Russian Chemical Bulletin
,  volume 64 ,  issue 6 ,  pages 1240-1248

Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease

Ya D Boyko 1, 2
, 
A Yu Sukhorukov 1
, 
S L Ioffe 1
, 
V.A. Tartakovsky 1
1
 
2
 
Higher Chemical College of the Russian Academy of Sciences, Moscow, Russian Federation | 
Publication type: Journal Article
Publication date: 2015-06-01
Springer Nature
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
The review summarizes the known approaches to diastereo- and enantioselective synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)hexahydro-3H-pyrrolizin-3-one (Pyrromilast), a highly active inhibitor of subtype 4B phosphodiesterase and a promising agent for treatment of chronic obstructive pulmonary disease.
Found 
Found 
3 citations
Sukhorukov Alexey
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Boyko Ya. D. et al. Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease // Russian Chemical Bulletin. 2015. Vol. 64. No. 6. pp. 1240-1248.
GOST all authors (up to 50) Copy
Boyko Ya. D., Sukhorukov A. Yu., Ioffe S. L., Tartakovsky V. Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease // Russian Chemical Bulletin. 2015. Vol. 64. No. 6. pp. 1240-1248.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s11172-015-1007-2
UR - https://doi.org/10.1007/s11172-015-1007-2
TI - Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease
T2 - Russian Chemical Bulletin
AU - Boyko, Ya D
AU - Sukhorukov, A Yu
AU - Ioffe, S L
AU - Tartakovsky, V.A.
PY - 2015
DA - 2015/06/01
PB - Springer Nature
SP - 1240-1248
IS - 6
VL - 64
SN - 1066-5285
SN - 1573-9171
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Boyko,
author = {Ya D Boyko and A Yu Sukhorukov and S L Ioffe and V.A. Tartakovsky},
title = {Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease},
journal = {Russian Chemical Bulletin},
year = {2015},
volume = {64},
publisher = {Springer Nature},
month = {jun},
url = {https://doi.org/10.1007/s11172-015-1007-2},
number = {6},
pages = {1240--1248},
doi = {10.1007/s11172-015-1007-2}
}
MLA
Cite this
MLA Copy
Boyko, Ya. D., et al. “Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease.” Russian Chemical Bulletin, vol. 64, no. 6, Jun. 2015, pp. 1240-1248. https://doi.org/10.1007/s11172-015-1007-2.