New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
V V Dotsenko
1, 2, 3
,
K A Frolov
3, 4
,
E A Chigorina
5
,
A N Khrustaleva
3
,
E Yu Bibik
4
,
S G Krivokolysko
3, 4
3
Scientific Research Laboratory “Khimeks”, Vladimir Dal’Lugansk National University, Lugansk, Ukraine
|
Publication type: Journal Article
Publication date: 2019-04-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
The review summarizes the results obtained by our research group over the past 15 years in chemistry of N-, S,N-, and Se,N-heterocycles resulted from aminomethlation of a wide range of acyclic and heterocyclic substrates derived from active methylene amides, thioamides, and selenoamides. A series of 1,3,5-thia(selena)diazines, 3,7-diazabicyclo[3.3.1] nonanes, 3,5,7,11-tetraazatricyclo[7.3.1.02,7]tridec-2-enes, 1,3,5,7-tetrazocines, and pyrido[1,2-a][1,3,5]triazines were synthesized. The general regularities of the Mannich reaction in the series of N-, S,N-, and Se,N-containing pyridine substrates were discussed. Biological activities of some synthesized compounds were studied to reveal compounds with antiviral, analeptic, anti-inflammatory, and antipyretic activities.
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Total citations:
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Citations from 2024:
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(27.78%)
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GOST
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Dotsenko V. V. et al. New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles // Russian Chemical Bulletin. 2019. Vol. 68. No. 4. pp. 691-707.
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Dotsenko V. V., Frolov K. A., Chigorina E. A., Khrustaleva A. N., Bibik E. Yu., Krivokolysko S. G. New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles // Russian Chemical Bulletin. 2019. Vol. 68. No. 4. pp. 691-707.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s11172-019-2476-5
UR - https://doi.org/10.1007/s11172-019-2476-5
TI - New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
T2 - Russian Chemical Bulletin
AU - Dotsenko, V V
AU - Frolov, K A
AU - Chigorina, E A
AU - Khrustaleva, A N
AU - Bibik, E Yu
AU - Krivokolysko, S G
PY - 2019
DA - 2019/04/01
PB - Springer Nature
SP - 691-707
IS - 4
VL - 68
SN - 1066-5285
SN - 1573-9171
ER -
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BibTex (up to 50 authors)
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@article{2019_Dotsenko,
author = {V V Dotsenko and K A Frolov and E A Chigorina and A N Khrustaleva and E Yu Bibik and S G Krivokolysko},
title = {New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles},
journal = {Russian Chemical Bulletin},
year = {2019},
volume = {68},
publisher = {Springer Nature},
month = {apr},
url = {https://doi.org/10.1007/s11172-019-2476-5},
number = {4},
pages = {691--707},
doi = {10.1007/s11172-019-2476-5}
}
Cite this
MLA
Copy
Dotsenko, V. V., et al. “New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles.” Russian Chemical Bulletin, vol. 68, no. 4, Apr. 2019, pp. 691-707. https://doi.org/10.1007/s11172-019-2476-5.
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