Determination of boron by inductively coupled plasma atomic emission spectroscopy. Biodistribution of 10B in tumor-bearing mice
A R Tsygankova
1, 2
,
V V Kanygin
1
,
A I Kasatova
1, 3
,
E L Zavyalov
1, 4
,
T Ya Guselnikova
2
,
A I Kichigin
1, 4
,
R A Mukhamadiyarov
5
Тип публикации: Journal Article
Дата публикации: 2020-03-01
scimago Q3
БС2
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Краткое описание
The determination of boron in animal organ tissues using inductively coupled plasma atomic emission spectroscopy (ICP AES) has been optimized for analytical support of boron neutron capture therapy of cancerous tumors. The proposed technique is universal and rapid. The methodology includes: preliminary acid decomposition at elevated temperatures and pressure (if necessary), determination of boron by ICP AES in the obtained solutions using reference samples based on single-element solutions. The method is verified by spike experiment and varying the weight-samples. The ICP AES technique was used to evaluate the accumulation of boronophenylalanine and borocaptate in mice organs. Biodistribution of 10B in the case of intravenous administration of the drug to SCID mice with SPF status using the human glioblastoma cell line U87 was investigated.
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Tsygankova A. R. et al. Determination of boron by inductively coupled plasma atomic emission spectroscopy. Biodistribution of 10B in tumor-bearing mice // Russian Chemical Bulletin. 2020. Vol. 69. No. 3. pp. 601-607.
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Tsygankova A. R., Kanygin V. V., Kasatova A. I., Zavyalov E. L., Guselnikova T. Ya., Kichigin A. I., Mukhamadiyarov R. A. Determination of boron by inductively coupled plasma atomic emission spectroscopy. Biodistribution of 10B in tumor-bearing mice // Russian Chemical Bulletin. 2020. Vol. 69. No. 3. pp. 601-607.
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TY - JOUR
DO - 10.1007/s11172-020-2805-8
UR - https://doi.org/10.1007/s11172-020-2805-8
TI - Determination of boron by inductively coupled plasma atomic emission spectroscopy. Biodistribution of 10B in tumor-bearing mice
T2 - Russian Chemical Bulletin
AU - Tsygankova, A R
AU - Kanygin, V V
AU - Kasatova, A I
AU - Zavyalov, E L
AU - Guselnikova, T Ya
AU - Kichigin, A I
AU - Mukhamadiyarov, R A
PY - 2020
DA - 2020/03/01
PB - Springer Nature
SP - 601-607
IS - 3
VL - 69
SN - 1066-5285
SN - 1573-9171
ER -
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@article{2020_Tsygankova,
author = {A R Tsygankova and V V Kanygin and A I Kasatova and E L Zavyalov and T Ya Guselnikova and A I Kichigin and R A Mukhamadiyarov},
title = {Determination of boron by inductively coupled plasma atomic emission spectroscopy. Biodistribution of 10B in tumor-bearing mice},
journal = {Russian Chemical Bulletin},
year = {2020},
volume = {69},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s11172-020-2805-8},
number = {3},
pages = {601--607},
doi = {10.1007/s11172-020-2805-8}
}
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MLA
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Tsygankova, A. R., et al. “Determination of boron by inductively coupled plasma atomic emission spectroscopy. Biodistribution of 10B in tumor-bearing mice.” Russian Chemical Bulletin, vol. 69, no. 3, Mar. 2020, pp. 601-607. https://doi.org/10.1007/s11172-020-2805-8.