Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines
Publication type: Journal Article
Publication date: 2020-11-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
The protolytic properties and reactions with molecular iodine and blood serum proteins of 5,7-dimethyltetrahydro-1H-imidazo[4,5-e]-1,2,4-triazine-3,6(2H,4H)-dithione and (R)-1,3-dialkyl-4-[(2-hydroxybenzylidene)amino]-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-ones were studied. These compounds exhibit different chemical reactivities towards molecular iodine. The binding constants between these compounds and serum albumin attest to a considerable protein affinity of the compounds. The properties of the thiones make them promising as antithyroid agents.
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Ivolgina V. A. et al. Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines // Russian Chemical Bulletin. 2020. Vol. 69. No. 11. pp. 2215-2221.
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Ivolgina V. A., POPOV L., Gazieva G. A., Kravchenko A. N. Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines // Russian Chemical Bulletin. 2020. Vol. 69. No. 11. pp. 2215-2221.
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TY - JOUR
DO - 10.1007/s11172-020-3024-z
UR - http://link.springer.com/10.1007/s11172-020-3024-z
TI - Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines
T2 - Russian Chemical Bulletin
AU - Ivolgina, V A
AU - POPOV, L.D.
AU - Gazieva, G A
AU - Kravchenko, A N
PY - 2020
DA - 2020/11/01
PB - Springer Nature
SP - 2215-2221
IS - 11
VL - 69
SN - 1066-5285
SN - 1573-9171
ER -
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@article{2020_Ivolgina,
author = {V A Ivolgina and L.D. POPOV and G A Gazieva and A N Kravchenko},
title = {Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines},
journal = {Russian Chemical Bulletin},
year = {2020},
volume = {69},
publisher = {Springer Nature},
month = {nov},
url = {http://link.springer.com/10.1007/s11172-020-3024-z},
number = {11},
pages = {2215--2221},
doi = {10.1007/s11172-020-3024-z}
}
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MLA
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Ivolgina, V. A., et al. “Protolytic and potential antithyroid properties of thioglycolurils and fused azolo-1,2,4-triazines.” Russian Chemical Bulletin, vol. 69, no. 11, Nov. 2020, pp. 2215-2221. http://link.springer.com/10.1007/s11172-020-3024-z.
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