Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group
Publication type: Journal Article
Publication date: 2021-01-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
A convenient method for the synthesis of C(28)-linker derivatives of triterpenoids containing a phosphonate group is presented. The method is based on the reaction of triterpenic acids (using betulinic acid as an example) with O, O -dialkyl-ω-bromoalkane phosphonates in DMF in the presence of K 2 CO 3 . The target phosphonates are synthesized in a yield of about 80%. The structures and compositions of the synthesized compounds were confirmed by NMR spectroscopy, IR spectroscopy, and elemental analysis.
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Tsepaeva O. V. et al. Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group // Russian Chemical Bulletin. 2021. Vol. 70. No. 1. pp. 179-182.
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Tsepaeva O. V., Nemtarev A. V., Grigoreva L. R., Mironov V. F. Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group // Russian Chemical Bulletin. 2021. Vol. 70. No. 1. pp. 179-182.
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TY - JOUR
DO - 10.1007/s11172-021-3074-x
UR - https://doi.org/10.1007/s11172-021-3074-x
TI - Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group
T2 - Russian Chemical Bulletin
AU - Tsepaeva, O V
AU - Nemtarev, A V
AU - Grigoreva, L R
AU - Mironov, V F
PY - 2021
DA - 2021/01/01
PB - Springer Nature
SP - 179-182
IS - 1
VL - 70
SN - 1066-5285
SN - 1573-9171
ER -
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BibTex (up to 50 authors)
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@article{2021_Tsepaeva,
author = {O V Tsepaeva and A V Nemtarev and L R Grigoreva and V F Mironov},
title = {Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group},
journal = {Russian Chemical Bulletin},
year = {2021},
volume = {70},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s11172-021-3074-x},
number = {1},
pages = {179--182},
doi = {10.1007/s11172-021-3074-x}
}
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MLA
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Tsepaeva, O. V., et al. “Synthesis of C(28)-linker derivatives of betulinic acid bearing phosphonate group.” Russian Chemical Bulletin, vol. 70, no. 1, Jan. 2021, pp. 179-182. https://doi.org/10.1007/s11172-021-3074-x.