Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa
A Yu Potapov
1
,
B V Paponov
2
,
N A Podoplelova
3
,
M A Panteleev
3
,
V A Polikarchuk
1
,
I V Ledenyova
1
,
N V Stolpovskaya
1
,
D V Krylskii
4
,
Kh S Shikhaliev
1
4
Research Institute of Applied Acoustics, Dubna, Moscow Region, Russian Federation
|
Publication type: Journal Article
Publication date: 2021-03-27
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
Condensation of 7-hydroxy-1,2,2,4-tetramethylhydroquinoline-6-carbaldehydes with various hetaryl-substituted 3-oxo esters afforded a series of hybrid hydro-6,8,8,9-tetramethyl-2H-pyrano[3,2-g]quinolin-2-ones. A number of these compounds exhibited relatively high inhibitory activity against blood coagulation factors Xa and XIa.
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Potapov A. Yu. et al. Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa // Russian Chemical Bulletin. 2021. Vol. 70. No. 3. pp. 492-497.
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Potapov A. Yu., Paponov B. V., Podoplelova N. A., Panteleev M. A., Polikarchuk V. A., Ledenyova I. V., Stolpovskaya N. V., Krylskii D. V., Shikhaliev Kh. S. Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa // Russian Chemical Bulletin. 2021. Vol. 70. No. 3. pp. 492-497.
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RIS
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TY - JOUR
DO - 10.1007/s11172-021-3114-6
UR - https://doi.org/10.1007/s11172-021-3114-6
TI - Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa
T2 - Russian Chemical Bulletin
AU - Potapov, A Yu
AU - Paponov, B V
AU - Podoplelova, N A
AU - Panteleev, M A
AU - Polikarchuk, V A
AU - Ledenyova, I V
AU - Stolpovskaya, N V
AU - Krylskii, D V
AU - Shikhaliev, Kh S
PY - 2021
DA - 2021/03/27
PB - Springer Nature
SP - 492-497
IS - 3
VL - 70
SN - 1066-5285
SN - 1573-9171
ER -
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BibTex (up to 50 authors)
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@article{2021_Potapov,
author = {A Yu Potapov and B V Paponov and N A Podoplelova and M A Panteleev and V A Polikarchuk and I V Ledenyova and N V Stolpovskaya and D V Krylskii and Kh S Shikhaliev},
title = {Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa},
journal = {Russian Chemical Bulletin},
year = {2021},
volume = {70},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s11172-021-3114-6},
number = {3},
pages = {492--497},
doi = {10.1007/s11172-021-3114-6}
}
Cite this
MLA
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Potapov, A. Yu., et al. “Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa.” Russian Chemical Bulletin, vol. 70, no. 3, Mar. 2021, pp. 492-497. https://doi.org/10.1007/s11172-021-3114-6.