Efficient synthesis of (5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the recyclization of N-arylitaconimides with 3-amino[1,2,4]triazoles
Publication type: Journal Article
Publication date: 2021-03-27
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
A convenient method for the synthesis of 2-(2-R-5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the regioselective domino reaction of N-arylitaconimides with substituted 3-aminotriazoles was proposed. Presumably, the reaction pathway includes the conjugated aza-addition of the endo-nucleophilic center of triazole to imide, followed by the recyclization of the intermediate to triazolo[1,5-a]pyrimidine.
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Kovygin Yu. A. et al. Efficient synthesis of (5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the recyclization of N-arylitaconimides with 3-amino[1,2,4]triazoles // Russian Chemical Bulletin. 2021. Vol. 70. No. 3. pp. 520-526.
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Kovygin Yu. A., Vandyshev D. Yu., Ledenyova I. V., Kosheleva E. A., Polikarchuk V. A., Kozaderov O. A., Shikhaliev Kh. S. Efficient synthesis of (5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the recyclization of N-arylitaconimides with 3-amino[1,2,4]triazoles // Russian Chemical Bulletin. 2021. Vol. 70. No. 3. pp. 520-526.
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TY - JOUR
DO - 10.1007/s11172-021-3118-2
UR - https://doi.org/10.1007/s11172-021-3118-2
TI - Efficient synthesis of (5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the recyclization of N-arylitaconimides with 3-amino[1,2,4]triazoles
T2 - Russian Chemical Bulletin
AU - Kovygin, Yu A
AU - Vandyshev, D Yu
AU - Ledenyova, I V
AU - Kosheleva, E A
AU - Polikarchuk, V A
AU - Kozaderov, O A
AU - Shikhaliev, Kh S
PY - 2021
DA - 2021/03/27
PB - Springer Nature
SP - 520-526
IS - 3
VL - 70
SN - 1066-5285
SN - 1573-9171
ER -
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@article{2021_Kovygin,
author = {Yu A Kovygin and D Yu Vandyshev and I V Ledenyova and E A Kosheleva and V A Polikarchuk and O A Kozaderov and Kh S Shikhaliev},
title = {Efficient synthesis of (5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the recyclization of N-arylitaconimides with 3-amino[1,2,4]triazoles},
journal = {Russian Chemical Bulletin},
year = {2021},
volume = {70},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s11172-021-3118-2},
number = {3},
pages = {520--526},
doi = {10.1007/s11172-021-3118-2}
}
Cite this
MLA
Copy
Kovygin, Yu. A., et al. “Efficient synthesis of (5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the recyclization of N-arylitaconimides with 3-amino[1,2,4]triazoles.” Russian Chemical Bulletin, vol. 70, no. 3, Mar. 2021, pp. 520-526. https://doi.org/10.1007/s11172-021-3118-2.