Russian Chemical Bulletin

, том 71 , издание 3 , страницы 543-548

Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application

I. V. Fadeeva ¹

A A Forysenkova ¹

E S Trofimchuk ²

M R Gafurov ³

A. I. Ahmed ^{3, 4}

G A Davidova ⁵

O. S. Antonova ¹

S. M. Barinov ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 5 аффилиаций

A. A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Moscow, Russian Federation |

M. V. Lomonosov Moscow State University, Moscow, Russian Federation |

Kazan Federal University, Kazan, Russian Federation |

⁴

Department of Physics, University of Al-Hamadaniya, Mosul, Iraq |

⁵

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russian Federation |

Тип публикации: Journal Article

Дата публикации: 2022-03-01

Springer Nature

Russian Chemical Bulletin

scimago Q3

БС2

SJR: 0.305

CiteScore: 2.8

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ISSN: 10665285, 15739171

DOI: 10.1007/s11172-022-3446-x

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General Chemistry

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A number of materials based on biocompatible polymers (polyvinylpyrrolidone and sodium alginate) with hydroxyapatite and dicalcium phosphate dihydrate were developed. The properties of prepared materials were studied by IR and EPR spectroscopies depending on the composition and method of synthesis of calcium phosphates. The introduction of calcium phosphates into the polymer matrix was found to decrease the material porosity from 60–70 to 40–45 vol.% and to decrease the material swelling from 250 to 150%. The results of EPR spectroscopy showed that polyvinylpyrrolidone does not affect the calcium phosphates formation in the synthesis of calcium phosphates in situ. In vitro studies suggest that a composition containing polyvinylpyrrolidone and sodium alginate in a ratio of 1 : 1 obtained ex situ is preferable in connection with its good biocompartability and an absence of cytotoxicity. This material is promising for the application in medicine.

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Fadeeva I. V. et al. Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application // Russian Chemical Bulletin. 2022. Vol. 71. No. 3. pp. 543-548.

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Fadeeva I. V., Forysenkova A. A., Trofimchuk E. S., Gafurov M. R., Ahmed A. I., Davidova G. A., Antonova O. S., Barinov S. M. Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application // Russian Chemical Bulletin. 2022. Vol. 71. No. 3. pp. 543-548.

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TY - JOUR

DO - 10.1007/s11172-022-3446-x

UR - https://doi.org/10.1007/s11172-022-3446-x

TI - Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application

T2 - Russian Chemical Bulletin

AU - Fadeeva, I. V.

AU - Forysenkova, A A

AU - Trofimchuk, E S

AU - Gafurov, M R

AU - Ahmed, A. I.

AU - Davidova, G A

AU - Antonova, O. S.

AU - Barinov, S. M.

PY - 2022

DA - 2022/03/01

PB - Springer Nature

SP - 543-548

IS - 3

VL - 71

SN - 1066-5285

SN - 1573-9171

ER -

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@article{2022_Fadeeva,

author = {I. V. Fadeeva and A A Forysenkova and E S Trofimchuk and M R Gafurov and A. I. Ahmed and G A Davidova and O. S. Antonova and S. M. Barinov},

title = {Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application},

journal = {Russian Chemical Bulletin},

year = {2022},

volume = {71},

publisher = {Springer Nature},

month = {mar},

url = {https://doi.org/10.1007/s11172-022-3446-x},

number = {3},

pages = {543--548},

doi = {10.1007/s11172-022-3446-x}

}

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Fadeeva, I. V., et al. “Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application.” Russian Chemical Bulletin, vol. 71, no. 3, Mar. 2022, pp. 543-548. https://doi.org/10.1007/s11172-022-3446-x.