Springer Nature
Russian Chemical Bulletin
,  volume 71 ,  issue 3 ,  pages 543-548

Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application

Publication type: Journal Article
Publication date: 2022-03-01
Springer Nature
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
A number of materials based on biocompatible polymers (polyvinylpyrrolidone and sodium alginate) with hydroxyapatite and dicalcium phosphate dihydrate were developed. The properties of prepared materials were studied by IR and EPR spectroscopies depending on the composition and method of synthesis of calcium phosphates. The introduction of calcium phosphates into the polymer matrix was found to decrease the material porosity from 60–70 to 40–45 vol.% and to decrease the material swelling from 250 to 150%. The results of EPR spectroscopy showed that polyvinylpyrrolidone does not affect the calcium phosphates formation in the synthesis of calcium phosphates in situ. In vitro studies suggest that a composition containing polyvinylpyrrolidone and sodium alginate in a ratio of 1 : 1 obtained ex situ is preferable in connection with its good biocompartability and an absence of cytotoxicity. This material is promising for the application in medicine.
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Fadeeva I. V. et al. Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application // Russian Chemical Bulletin. 2022. Vol. 71. No. 3. pp. 543-548.
GOST all authors (up to 50) Copy
Fadeeva I. V., Forysenkova A. A., Trofimchuk E. S., Gafurov M. R., Ahmed A. I., Davidova G. A., Antonova O. S., Barinov S. M. Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application // Russian Chemical Bulletin. 2022. Vol. 71. No. 3. pp. 543-548.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1007/s11172-022-3446-x
UR - https://doi.org/10.1007/s11172-022-3446-x
TI - Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application
T2 - Russian Chemical Bulletin
AU - Fadeeva, I. V.
AU - Forysenkova, A A
AU - Trofimchuk, E S
AU - Gafurov, M R
AU - Ahmed, A. I.
AU - Davidova, G A
AU - Antonova, O. S.
AU - Barinov, S. M.
PY - 2022
DA - 2022/03/01
PB - Springer Nature
SP - 543-548
IS - 3
VL - 71
SN - 1066-5285
SN - 1573-9171
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Fadeeva,
author = {I. V. Fadeeva and A A Forysenkova and E S Trofimchuk and M R Gafurov and A. I. Ahmed and G A Davidova and O. S. Antonova and S. M. Barinov},
title = {Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application},
journal = {Russian Chemical Bulletin},
year = {2022},
volume = {71},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s11172-022-3446-x},
number = {3},
pages = {543--548},
doi = {10.1007/s11172-022-3446-x}
}
MLA
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MLA Copy
Fadeeva, I. V., et al. “Porous matrixes based on polyvinylpyrrolidone containing calcium phosphates for medical application.” Russian Chemical Bulletin, vol. 71, no. 3, Mar. 2022, pp. 543-548. https://doi.org/10.1007/s11172-022-3446-x.