volume 72 issue 1 pages 103-129

Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis

Publication typeJournal Article
Publication date2023-01-01
scimago Q3
SJR0.305
CiteScore2.8
Impact factor
ISSN10665285, 15739171
General Chemistry
Abstract
The review is summarized and systematized the published data on the multicomponent reactions of ethyl trifluoroacetoacetate, carbonyl compounds (aldehydes and ketones), and nucleophilic reagents. The recent advances in the study of the Hantzsch and Biginelli reactions involving polyfluoroalkyl-3-oxo esters are analyzed. These transformations tolerated a broad range of the nucleophilic reagents thus allowing the synthesis of a wide variety of hetero- and carbocyclic compounds including the derivatives of pyridine, pyrimidine, pyrazole, pyran, dioxane, and isoxazole as well as their heterofused derivatives. The reactivity characteristics of ethyl trifluoroacetoacetate with different reagents in these multicomponent transformations are discussed.
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GOST Copy
Kushch S. O. et al. Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis // Russian Chemical Bulletin. 2023. Vol. 72. No. 1. pp. 103-129.
GOST all authors (up to 50) Copy
Kushch S. O., Goryaeva M. V., Burgart Y. V., Saloutin V. I. Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis // Russian Chemical Bulletin. 2023. Vol. 72. No. 1. pp. 103-129.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1007/s11172-023-3717-1
UR - https://doi.org/10.1007/s11172-023-3717-1
TI - Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis
T2 - Russian Chemical Bulletin
AU - Kushch, S. O.
AU - Goryaeva, M. V.
AU - Burgart, Ya. V.
AU - Saloutin, V. I.
PY - 2023
DA - 2023/01/01
PB - Springer Nature
SP - 103-129
IS - 1
VL - 72
SN - 1066-5285
SN - 1573-9171
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Kushch,
author = {S. O. Kushch and M. V. Goryaeva and Ya. V. Burgart and V. I. Saloutin},
title = {Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis},
journal = {Russian Chemical Bulletin},
year = {2023},
volume = {72},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s11172-023-3717-1},
number = {1},
pages = {103--129},
doi = {10.1007/s11172-023-3717-1}
}
MLA
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MLA Copy
Kushch, S. O., et al. “Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis.” Russian Chemical Bulletin, vol. 72, no. 1, Jan. 2023, pp. 103-129. https://doi.org/10.1007/s11172-023-3717-1.