Springer Nature
Russian Chemical Bulletin
,  том 72 ,  издание 9 ,  страницы 1972-1990

Antioxidant activity of Mannich bases derived from natural and synthetic phenols

Тип публикации: Journal Article
Дата публикации: 2023-09-26
Springer Nature
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SJR: 0.272
CiteScore: 2.8
Impact factor: 1.6
ISSN: 10665285, 15739171
General Chemistry
Краткое описание
The data obtained earlier on the Mannich bases derived from natural and synthetic phenols are summarized, the structure—antioxidant activity relationship is analyzed, and the most active compounds among these bases are identified. The influence of the nature and position of aminomethyl substituents on the hemolytic activity (erythrotoxicity) is considered. The high antioxidant and membrane-protective activity exhibited by some Mannich bases in the model of oxidative hemolysis of mammalian erythrocytes is explained by the presence in their structure of a N-alkyl group or a fragment of a heterocyclic amine, which affects the lipophilicity of the compounds and the interaction with the cell membrane.
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SHEVCHENKO O. G., Buravlev E. V. Antioxidant activity of Mannich bases derived from natural and synthetic phenols // Russian Chemical Bulletin. 2023. Vol. 72. No. 9. pp. 1972-1990.
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SHEVCHENKO O. G., Buravlev E. V. Antioxidant activity of Mannich bases derived from natural and synthetic phenols // Russian Chemical Bulletin. 2023. Vol. 72. No. 9. pp. 1972-1990.
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TY - JOUR
DO - 10.1007/s11172-023-3991-y
UR - https://doi.org/10.1007/s11172-023-3991-y
TI - Antioxidant activity of Mannich bases derived from natural and synthetic phenols
T2 - Russian Chemical Bulletin
AU - SHEVCHENKO, O. G.
AU - Buravlev, E V
PY - 2023
DA - 2023/09/26
PB - Springer Nature
SP - 1972-1990
IS - 9
VL - 72
SN - 1066-5285
SN - 1573-9171
ER -
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@article{2023_SHEVCHENKO,
author = {O. G. SHEVCHENKO and E V Buravlev},
title = {Antioxidant activity of Mannich bases derived from natural and synthetic phenols},
journal = {Russian Chemical Bulletin},
year = {2023},
volume = {72},
publisher = {Springer Nature},
month = {sep},
url = {https://doi.org/10.1007/s11172-023-3991-y},
number = {9},
pages = {1972--1990},
doi = {10.1007/s11172-023-3991-y}
}
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SHEVCHENKO, O. G., and E V Buravlev. “Antioxidant activity of Mannich bases derived from natural and synthetic phenols.” Russian Chemical Bulletin, vol. 72, no. 9, Sep. 2023, pp. 1972-1990. https://doi.org/10.1007/s11172-023-3991-y.
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