3-Oxabicyclo[3.3.1]nonenes: synthesis and investigation as tyrosyl-DNA phosphodiesterase 1 inhibitors
Publication type: Journal Article
Publication date: 2023-10-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
Compounds with a 3-oxabicyclo[3.3.1]nonane core were prepared from limonene and aromatic aldehydes containing methoxy groups and phthalaldehydes in the presence of montmorillonite K10 and were converted to aromatic amines containing this heterocycle. Some of the products were found to exhibit inhibitory activity in the reaction catalyzed by human tyrosyl-DNA phosphodiesterase 1 in the micromolar range. Bromo derivatives of amines, compounds 6b and 7b, which combine high inhibitory activity and low cytotoxicity, are promising for further studies in order to create new agents for the use in combined anticancer therapy.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
Russian Chemical Bulletin
4 publications, 44.44%
|
|
|
Журнал Общей Химии
2 publications, 22.22%
|
|
|
Russian Chemical Reviews
1 publication, 11.11%
|
|
|
Journal of Organic Chemistry
1 publication, 11.11%
|
|
|
Tetrahedron
1 publication, 11.11%
|
|
|
1
2
3
4
|
Publishers
|
1
2
3
4
|
|
|
Springer Nature
4 publications, 44.44%
|
|
|
The Russian Academy of Sciences
2 publications, 22.22%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 11.11%
|
|
|
American Chemical Society (ACS)
1 publication, 11.11%
|
|
|
Elsevier
1 publication, 11.11%
|
|
|
1
2
3
4
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
9
Total citations:
9
Citations from 2024:
9
(100%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Dyrkheeva N. S. et al. 3-Oxabicyclo[3.3.1]nonenes: synthesis and investigation as tyrosyl-DNA phosphodiesterase 1 inhibitors // Russian Chemical Bulletin. 2023. Vol. 72. No. 10. pp. 2525-2535.
GOST all authors (up to 50)
Copy
Dyrkheeva N. S., Ilyina I. V., Volcho K. P., Salakhutdinov N. F., Lavrik O. I. 3-Oxabicyclo[3.3.1]nonenes: synthesis and investigation as tyrosyl-DNA phosphodiesterase 1 inhibitors // Russian Chemical Bulletin. 2023. Vol. 72. No. 10. pp. 2525-2535.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s11172-023-4055-z
UR - https://doi.org/10.1007/s11172-023-4055-z
TI - 3-Oxabicyclo[3.3.1]nonenes: synthesis and investigation as tyrosyl-DNA phosphodiesterase 1 inhibitors
T2 - Russian Chemical Bulletin
AU - Dyrkheeva, N S
AU - Ilyina, I V
AU - Volcho, K P
AU - Salakhutdinov, N. F.
AU - Lavrik, O I
PY - 2023
DA - 2023/10/01
PB - Springer Nature
SP - 2525-2535
IS - 10
VL - 72
SN - 1066-5285
SN - 1573-9171
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_Dyrkheeva,
author = {N S Dyrkheeva and I V Ilyina and K P Volcho and N. F. Salakhutdinov and O I Lavrik},
title = {3-Oxabicyclo[3.3.1]nonenes: synthesis and investigation as tyrosyl-DNA phosphodiesterase 1 inhibitors},
journal = {Russian Chemical Bulletin},
year = {2023},
volume = {72},
publisher = {Springer Nature},
month = {oct},
url = {https://doi.org/10.1007/s11172-023-4055-z},
number = {10},
pages = {2525--2535},
doi = {10.1007/s11172-023-4055-z}
}
Cite this
MLA
Copy
Dyrkheeva, N. S., et al. “3-Oxabicyclo[3.3.1]nonenes: synthesis and investigation as tyrosyl-DNA phosphodiesterase 1 inhibitors.” Russian Chemical Bulletin, vol. 72, no. 10, Oct. 2023, pp. 2525-2535. https://doi.org/10.1007/s11172-023-4055-z.
Profiles