Synthesis of (1S)-(+)-camphor-10-sulfonamides and evaluation of their anti-filovirus activity
A.S. Sokolova
1
,
D V Baranova
1
,
O. I. Yarovaya
1
,
A V Zybkina
2
,
E. D. Mordvinova
2
,
A V Zaykovskaya
2
,
D. S. Baev
1
,
T G Tolstikova
1
,
D. N. Shcherbakov
2
,
O V Pyankov
2
,
R A Maksyutov
2
,
N. F. Salakhutdinov
1
Publication type: Journal Article
Publication date: 2023-10-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
General Chemistry
Abstract
A series of new (1S)-(+)-camphor-10-sulfonamides containing various substituents at the nitrogen atom were synthesized, and their antiviral properties against Ebola virus were evaluated using a vesicular stomatitis virus-based pseudovirus system. The reduction of the carbonyl group at the C(2) atom leads to a significant improvement in the antiviral efficacy, whereas the transformation into oxime results in the almost complete disappearance of antiviral activity. According to the evaluation of antiviral activity against natural Ebola virus, the lead compounds exhibit moderate inhibitory activity. Interactions of the lead compounds with the binding site of Ebola virus glycoprotein were studied by molecular modeling. A comparative analysis of the changes due to possible interactions of the synthesized ligands and known inhibitors with Ebola virus surface glycoprotein was carried out.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
5
6
|
|
|
Russian Chemical Bulletin
6 publications, 54.55%
|
|
|
Журнал Общей Химии
2 publications, 18.18%
|
|
|
Russian Journal of General Chemistry
1 publication, 9.09%
|
|
|
European Journal of Medicinal Chemistry
1 publication, 9.09%
|
|
|
Russian Chemical Reviews
1 publication, 9.09%
|
|
|
1
2
3
4
5
6
|
Publishers
|
1
2
3
4
5
6
|
|
|
Springer Nature
6 publications, 54.55%
|
|
|
Pleiades Publishing
2 publications, 18.18%
|
|
|
Elsevier
1 publication, 9.09%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 9.09%
|
|
|
The Russian Academy of Sciences
1 publication, 9.09%
|
|
|
1
2
3
4
5
6
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
11
Total citations:
11
Citations from 2024:
9
(81.81%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Sokolova A. et al. Synthesis of (1S)-(+)-camphor-10-sulfonamides and evaluation of their anti-filovirus activity // Russian Chemical Bulletin. 2023. Vol. 72. No. 10. pp. 2536-2547.
GOST all authors (up to 50)
Copy
Sokolova A., Baranova D. V., Yarovaya O. I., Zybkina A. V., Mordvinova E. D., Zaykovskaya A. V., Baev D. S., Tolstikova T. G., Shcherbakov D. N., Pyankov O. V., Maksyutov R. A., Salakhutdinov N. F. Synthesis of (1S)-(+)-camphor-10-sulfonamides and evaluation of their anti-filovirus activity // Russian Chemical Bulletin. 2023. Vol. 72. No. 10. pp. 2536-2547.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s11172-023-4056-y
UR - https://doi.org/10.1007/s11172-023-4056-y
TI - Synthesis of (1S)-(+)-camphor-10-sulfonamides and evaluation of their anti-filovirus activity
T2 - Russian Chemical Bulletin
AU - Sokolova, A.S.
AU - Baranova, D V
AU - Yarovaya, O. I.
AU - Zybkina, A V
AU - Mordvinova, E. D.
AU - Zaykovskaya, A V
AU - Baev, D. S.
AU - Tolstikova, T G
AU - Shcherbakov, D. N.
AU - Pyankov, O V
AU - Maksyutov, R A
AU - Salakhutdinov, N. F.
PY - 2023
DA - 2023/10/01
PB - Springer Nature
SP - 2536-2547
IS - 10
VL - 72
SN - 1066-5285
SN - 1573-9171
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_Sokolova,
author = {A.S. Sokolova and D V Baranova and O. I. Yarovaya and A V Zybkina and E. D. Mordvinova and A V Zaykovskaya and D. S. Baev and T G Tolstikova and D. N. Shcherbakov and O V Pyankov and R A Maksyutov and N. F. Salakhutdinov},
title = {Synthesis of (1S)-(+)-camphor-10-sulfonamides and evaluation of their anti-filovirus activity},
journal = {Russian Chemical Bulletin},
year = {2023},
volume = {72},
publisher = {Springer Nature},
month = {oct},
url = {https://doi.org/10.1007/s11172-023-4056-y},
number = {10},
pages = {2536--2547},
doi = {10.1007/s11172-023-4056-y}
}
Cite this
MLA
Copy
Sokolova, A.S., et al. “Synthesis of (1S)-(+)-camphor-10-sulfonamides and evaluation of their anti-filovirus activity.” Russian Chemical Bulletin, vol. 72, no. 10, Oct. 2023, pp. 2536-2547. https://doi.org/10.1007/s11172-023-4056-y.
Profiles