Russian Chemical Bulletin

, том 73 , издание 5 , страницы 1408-1416

Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents

Тип публикации: Journal Article

Дата публикации: 2024-05-01

Springer Nature

Russian Chemical Bulletin

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white level БС2

SJR: 0.305

CiteScore: 2.8

Impact factor: 1.7

ISSN: 10665285, 15739171

DOI: 10.1007/s11172-024-4259-x

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A series of N-heterocyclic analogs of muricadienin, a precursor of various acetogenins, were synthesized, and their biological activity was studied. It was revealed that the linking group between the N-methylpyrazole/imidazole part and the hydrophobic alkadienyl chain affects the ability of these compounds to induce apoptosis and cause cell cycle arrest. Compound 3b showed the highest cytotoxic activity.

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Tuktarova R. A. et al. Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents // Russian Chemical Bulletin. 2024. Vol. 73. No. 5. p. 1408-1416.

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Tuktarova R. A., Dzhemileva L. U., Dzhemilev U. M., Dyakonov V. A. Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents // Russian Chemical Bulletin. 2024. Vol. 73. No. 5. p. 1408-1416.

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TY - JOUR

DO - 10.1007/s11172-024-4259-x

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196521693&origin=inward

TI - Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents

T2 - Russian Chemical Bulletin

AU - Tuktarova, R A

AU - Dzhemileva, L U

AU - Dzhemilev, U M

AU - Dyakonov, V A

PY - 2024

DA - 2024/05/01

PB - Springer Nature

SP - 1408-1416

IS - 5

VL - 73

SN - 1066-5285

SN - 1573-9171

ER -

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@article{2024_Tuktarova,

author = {R A Tuktarova and L U Dzhemileva and U M Dzhemilev and V A Dyakonov},

title = {Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents},

journal = {Russian Chemical Bulletin},

year = {2024},

volume = {73},

publisher = {Springer Nature},

month = {may},

url = {https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196521693&origin=inward},

number = {5},

pages = {1408--1416},

doi = {10.1007/s11172-024-4259-x}

}

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Tuktarova, R. A., et al. “Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents.” Russian Chemical Bulletin, vol. 73, no. 5, May. 2024, pp. 1408-1416. https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196521693&origin=inward.