Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents
Publication type: Journal Article
Publication date: 2024-05-01
scimago Q3
SJR: 0.305
CiteScore: 2.8
Impact factor: —
ISSN: 10665285, 15739171
Abstract
A series of N-heterocyclic analogs of muricadienin, a precursor of various acetogenins, were synthesized, and their biological activity was studied. It was revealed that the linking group between the N-methylpyrazole/imidazole part and the hydrophobic alkadienyl chain affects the ability of these compounds to induce apoptosis and cause cell cycle arrest. Compound 3b showed the highest cytotoxic activity.
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Russian Chemical Bulletin
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
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3
Total citations:
3
Citations from 2024:
3
(100%)
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Tuktarova R. A. et al. Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents // Russian Chemical Bulletin. 2024. Vol. 73. No. 5. p. 1408-1416.
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Tuktarova R. A., Dzhemileva L. U., Dzhemilev U. M., Dyakonov V. A. Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents // Russian Chemical Bulletin. 2024. Vol. 73. No. 5. p. 1408-1416.
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TY - JOUR
DO - 10.1007/s11172-024-4259-x
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196521693&origin=inward
TI - Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents
T2 - Russian Chemical Bulletin
AU - Tuktarova, R A
AU - Dzhemileva, L U
AU - Dzhemilev, U M
AU - Dyakonov, V A
PY - 2024
DA - 2024/05/01
PB - Springer Nature
SP - 1408-1416
IS - 5
VL - 73
SN - 1066-5285
SN - 1573-9171
ER -
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BibTex (up to 50 authors)
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@article{2024_Tuktarova,
author = {R A Tuktarova and L U Dzhemileva and U M Dzhemilev and V A Dyakonov},
title = {Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents},
journal = {Russian Chemical Bulletin},
year = {2024},
volume = {73},
publisher = {Springer Nature},
month = {may},
url = {https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196521693&origin=inward},
number = {5},
pages = {1408--1416},
doi = {10.1007/s11172-024-4259-x}
}
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MLA
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Tuktarova, R. A., et al. “Synthesis of N-heterocyclic analogs of natural muricadienin — promising antitumor agents.” Russian Chemical Bulletin, vol. 73, no. 5, May. 2024, pp. 1408-1416. https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196521693&origin=inward.
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