volume 33 issue 6 pages 2023-2032

Quantum-chemical study of organic reaction mechanisms. XI.*1 Biologically active 4-substituted 1,2,4-triazoles from diformylhydrazine and aminophenols

Publication typeJournal Article
Publication date2022-06-07
scimago Q3
wos Q2
SJR0.341
CiteScore4.3
Impact factor2.2
ISSN10400400, 15729001
Physical and Theoretical Chemistry
Condensed Matter Physics
Abstract
Derivatives of 1,2,4-triazole exhibit antimicrobial, anticonvulsant, anti-inflammatory, immunomodulatory, and other types of activity, which makes it possible to create effective drugs on their basis. Understanding the reaction mechanism for the formation of triazoles helps to control the chemical process and conduct targeted synthesis. Quantum-chemical modeling of the mechanism of interaction of diformylhydrazine with o- and p-aminophenols was carried out using the combined approach CCSD (T)/6–31+G*//B3LYP/6–311++G**. The elementary stages of the reaction, possible intermediate compounds, and transition states have been established. The obtained results have been compared with the data from NMR spectroscopy.
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Chirkina E., Larina L. I. Quantum-chemical study of organic reaction mechanisms. XI.*1 Biologically active 4-substituted 1,2,4-triazoles from diformylhydrazine and aminophenols // Structural Chemistry. 2022. Vol. 33. No. 6. pp. 2023-2032.
GOST all authors (up to 50) Copy
Chirkina E., Larina L. I. Quantum-chemical study of organic reaction mechanisms. XI.*1 Biologically active 4-substituted 1,2,4-triazoles from diformylhydrazine and aminophenols // Structural Chemistry. 2022. Vol. 33. No. 6. pp. 2023-2032.
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TY - JOUR
DO - 10.1007/s11224-022-01969-1
UR - https://doi.org/10.1007/s11224-022-01969-1
TI - Quantum-chemical study of organic reaction mechanisms. XI.*1 Biologically active 4-substituted 1,2,4-triazoles from diformylhydrazine and aminophenols
T2 - Structural Chemistry
AU - Chirkina, Elena
AU - Larina, Lyudmila I.
PY - 2022
DA - 2022/06/07
PB - Springer Nature
SP - 2023-2032
IS - 6
VL - 33
SN - 1040-0400
SN - 1572-9001
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2022_Chirkina,
author = {Elena Chirkina and Lyudmila I. Larina},
title = {Quantum-chemical study of organic reaction mechanisms. XI.*1 Biologically active 4-substituted 1,2,4-triazoles from diformylhydrazine and aminophenols},
journal = {Structural Chemistry},
year = {2022},
volume = {33},
publisher = {Springer Nature},
month = {jun},
url = {https://doi.org/10.1007/s11224-022-01969-1},
number = {6},
pages = {2023--2032},
doi = {10.1007/s11224-022-01969-1}
}
MLA
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Chirkina, Elena, et al. “Quantum-chemical study of organic reaction mechanisms. XI.*1 Biologically active 4-substituted 1,2,4-triazoles from diformylhydrazine and aminophenols.” Structural Chemistry, vol. 33, no. 6, Jun. 2022, pp. 2023-2032. https://doi.org/10.1007/s11224-022-01969-1.