Open Access
Bousmekines A-E, New Alkaloids from Two Bousigonia Species: B.angustifolia and B. mekongensis
Publication type: Journal Article
Publication date: 2020-11-03
scimago Q1
wos Q1
SJR: 1.067
CiteScore: 8.5
Impact factor: 4.9
ISSN: 21922195, 21922209
PubMed ID:
33140311
Organic Chemistry
Biochemistry
Pharmacology
Plant Science
Analytical Chemistry
Food Science
Toxicology
Abstract
Four new monoterpenoid indole alkaloids, bousmekines A-D (1–4), and one new pyranopyridine alkaloid, bousmekine E (5), were isolated from the twigs and leaves of Bousigonia angustifolia and Bousigonia mekongensis. Their structures including absolute configurations were elucidated by a combination of MS, NMR, ECD calculation, and single-crystal X-ray diffraction analysis. Compound 2 was an eburnea-type MIAs characterized by a rare chlorine atom while 5 possessed a novel pyranopyridine moiety. Their cytotoxicities against several human cancer cell lines were evaluated and compound 1 exhibited significant cytotoxicity with IC50 values of 0.8–7.4 μM.
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Huo Z. Q. et al. Bousmekines A-E, New Alkaloids from Two Bousigonia Species: B.angustifolia and B. mekongensis // Natural Products and Bioprospecting. 2020. Vol. 11. No. 2. pp. 207-213.
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Huo Z. Q., Zhao Q., Zhu W., Hao X., Gu Y. Bousmekines A-E, New Alkaloids from Two Bousigonia Species: B.angustifolia and B. mekongensis // Natural Products and Bioprospecting. 2020. Vol. 11. No. 2. pp. 207-213.
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RIS
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TY - JOUR
DO - 10.1007/s13659-020-00278-6
UR - https://doi.org/10.1007/s13659-020-00278-6
TI - Bousmekines A-E, New Alkaloids from Two Bousigonia Species: B.angustifolia and B. mekongensis
T2 - Natural Products and Bioprospecting
AU - Huo, Zong Qing
AU - Zhao, Qian
AU - Zhu, Wen-Tao
AU - Hao, Xiao-Jiang
AU - Gu, Yucheng
PY - 2020
DA - 2020/11/03
PB - Springer Nature
SP - 207-213
IS - 2
VL - 11
PMID - 33140311
SN - 2192-2195
SN - 2192-2209
ER -
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BibTex (up to 50 authors)
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@article{2020_Huo,
author = {Zong Qing Huo and Qian Zhao and Wen-Tao Zhu and Xiao-Jiang Hao and Yucheng Gu},
title = {Bousmekines A-E, New Alkaloids from Two Bousigonia Species: B.angustifolia and B. mekongensis},
journal = {Natural Products and Bioprospecting},
year = {2020},
volume = {11},
publisher = {Springer Nature},
month = {nov},
url = {https://doi.org/10.1007/s13659-020-00278-6},
number = {2},
pages = {207--213},
doi = {10.1007/s13659-020-00278-6}
}
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MLA
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Huo, Zong Qing, et al. “Bousmekines A-E, New Alkaloids from Two Bousigonia Species: B.angustifolia and B. mekongensis.” Natural Products and Bioprospecting, vol. 11, no. 2, Nov. 2020, pp. 207-213. https://doi.org/10.1007/s13659-020-00278-6.