Open Access
Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose
Raphael Allgaier
1
,
Arne Kandulski
2
,
Karsten Gülow
2
,
Lars Maier
1
,
Martina Müller
2
,
Hauke Christian Tews
2
Publication type: Journal Article
Publication date: 2023-03-29
scimago Q2
wos Q3
SJR: 0.691
CiteScore: 4.1
Impact factor: 2.1
ISSN: 11745886, 11796901
PubMed ID:
36988798
Pharmacology
Abstract
Metamizole is a non-opioid ampyrone sulfonate compound with potent analgesic, antipyretic, and spasmolytic effects. Agranulocytosis is a rare life-threatening complication of metamizole. Here, we present the case of a 62-year-old patient who developed agranulocytosis as well as hemolysis after a single administration of metamizole. This case illustrates the inherent allergic potential of metamizole and its effects on different hematopoietic cell types.
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Allgaier R. et al. Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose // Drugs in R and D. 2023. Vol. 23. No. 2. pp. 93-98.
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Allgaier R., Kandulski A., Gülow K., Maier L., Müller M., Tews H. C. Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose // Drugs in R and D. 2023. Vol. 23. No. 2. pp. 93-98.
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RIS
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TY - JOUR
DO - 10.1007/s40268-023-00415-9
UR - https://doi.org/10.1007/s40268-023-00415-9
TI - Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose
T2 - Drugs in R and D
AU - Allgaier, Raphael
AU - Kandulski, Arne
AU - Gülow, Karsten
AU - Maier, Lars
AU - Müller, Martina
AU - Tews, Hauke Christian
PY - 2023
DA - 2023/03/29
PB - Springer Nature
SP - 93-98
IS - 2
VL - 23
PMID - 36988798
SN - 1174-5886
SN - 1179-6901
ER -
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BibTex (up to 50 authors)
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@article{2023_Allgaier,
author = {Raphael Allgaier and Arne Kandulski and Karsten Gülow and Lars Maier and Martina Müller and Hauke Christian Tews},
title = {Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose},
journal = {Drugs in R and D},
year = {2023},
volume = {23},
publisher = {Springer Nature},
month = {mar},
url = {https://doi.org/10.1007/s40268-023-00415-9},
number = {2},
pages = {93--98},
doi = {10.1007/s40268-023-00415-9}
}
Cite this
MLA
Copy
Allgaier, Raphael, et al. “Case Report: Simultaneously Induced Neutropenia and Hemolysis After a Single Metamizole Dose.” Drugs in R and D, vol. 23, no. 2, Mar. 2023, pp. 93-98. https://doi.org/10.1007/s40268-023-00415-9.