Photochemical and Photobiological Sciences, volume 21, issue 5, pages 879-898
Lights on 2,5-diaryl tetrazoles: applications and limits of a versatile photoclick reaction
Publication type: Journal Article
Publication date: 2022-02-21
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor: 3.1
ISSN: 1474905X, 14749092
Physical and Theoretical Chemistry
Abstract
Recently, photoclick chemistry emerged as a powerful tool employed in several research fields, from medicinal chemistry and biology to material sciences. The growing interest in this type of chemical process is justified by the possibility to produce complex molecular systems using mild reaction conditions. However, the elevated spatio-temporal control offered by photoclick chemistry is highly intriguing, as it expands the range of applications. In this context, the light-triggered reaction of 2,5-diaryl tetrazoles with dipolarophiles emerged for its interesting features: excellent stability of the substrates, fast reaction kinetic, and the formation of a highly fluorescent product, fundamental for sensing applications. In the last years, 2,5-diaryl tetrazoles have been extensively employed, especially for bioorthogonal ligations, to label biomolecules and nucleic acids. In this review, we summarized recent applications of this interesting photoclick reaction, with a particular focus on biological fields. Moreover, we described the main limits that affect this system and current strategies proposed to overcome these issues. The general discussion here presented could prompt further optimization of the process and pave the way for the development of new original structures and innovative applications.
Top-30
Citations by journals
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1
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Journal of Physical Chemistry A
1 publication, 10%
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Chemical Science
1 publication, 10%
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Analytical and Bioanalytical Chemistry
1 publication, 10%
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Bioconjugate Chemistry
1 publication, 10%
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Advanced Functional Materials
1 publication, 10%
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ACS Applied Bio Materials
1 publication, 10%
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European Journal of Organic Chemistry
1 publication, 10%
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Russian Chemical Reviews
1 publication, 10%
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Tissue Engineering - Part B: Reviews
1 publication, 10%
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European Journal of Medicinal Chemistry
1 publication, 10%
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1
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Citations by publishers
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1
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3
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American Chemical Society (ACS)
3 publications, 30%
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Wiley
2 publications, 20%
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Royal Society of Chemistry (RSC)
1 publication, 10%
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Springer Nature
1 publication, 10%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 10%
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Mary Ann Liebert
1 publication, 10%
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Elsevier
1 publication, 10%
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Pirota V., Benassi A., DORIA F. Lights on 2,5-diaryl tetrazoles: applications and limits of a versatile photoclick reaction // Photochemical and Photobiological Sciences. 2022. Vol. 21. No. 5. pp. 879-898.
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Pirota V., Benassi A., DORIA F. Lights on 2,5-diaryl tetrazoles: applications and limits of a versatile photoclick reaction // Photochemical and Photobiological Sciences. 2022. Vol. 21. No. 5. pp. 879-898.
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TY - JOUR
DO - 10.1007/s43630-022-00173-8
UR - https://doi.org/10.1007/s43630-022-00173-8
TI - Lights on 2,5-diaryl tetrazoles: applications and limits of a versatile photoclick reaction
T2 - Photochemical and Photobiological Sciences
AU - Pirota, Valentina
AU - Benassi, Alessandra
AU - DORIA, FILIPPO
PY - 2022
DA - 2022/02/21 00:00:00
PB - Springer Nature
SP - 879-898
IS - 5
VL - 21
SN - 1474-905X
SN - 1474-9092
ER -
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@article{2022_Pirota,
author = {Valentina Pirota and Alessandra Benassi and FILIPPO DORIA},
title = {Lights on 2,5-diaryl tetrazoles: applications and limits of a versatile photoclick reaction},
journal = {Photochemical and Photobiological Sciences},
year = {2022},
volume = {21},
publisher = {Springer Nature},
month = {feb},
url = {https://doi.org/10.1007/s43630-022-00173-8},
number = {5},
pages = {879--898},
doi = {10.1007/s43630-022-00173-8}
}
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Pirota, Valentina, et al. “Lights on 2,5-diaryl tetrazoles: applications and limits of a versatile photoclick reaction.” Photochemical and Photobiological Sciences, vol. 21, no. 5, Feb. 2022, pp. 879-898. https://doi.org/10.1007/s43630-022-00173-8.