Elsevier
Steroids
,  том 36 ,  издание 2 ,  страницы 131-147

Species differences in biotransformation of 17α-cyanomethylestradiol 3-methyl ether

Тип публикации: Journal Article
Дата публикации: 1980-08-01
Elsevier
SCImago Q2
WOS Q3
БС2
SJR: 0.631
CiteScore: 4.8
Impact factor: 2.7
ISSN: 0039128X, 18785867
Organic Chemistry
Biochemistry
Molecular Biology
Pharmacology
Clinical Biochemistry
Endocrinology
Краткое описание
Following oral administration of 9,11-3H-17 alpha-cyanomethylestra-1,3,5(10)-triene-3,17-diol 3-methyl ether, urinary metabolites were studied in man, baboon, beagle dog, minipig and rat. The metabolite pattern revealed remarkable species differences, especially in quantitative respects. 17 alpha-Cyanomethylestra-1,3,5(10)triene-3,17-diol, 17 alpha-cyanomethylestra-1,3,5(10)-triene-2,3,17-triol 2-methyl ether, 17 alpha-hydroxymethylestra-1,3,5(10)-triene-3,17-diol and 17 alpha-cyanomethylestra-1,3,5(10)-triene-3,16 xi, 17-triol were isolated as principal metabolites. In rat bile, a metabolite was tentatively identified as a gamma-lactone of a 17 alpha-carboxymethyl-16 alpha-hydroxy compound.
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ГОСТ |
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Hobe G., Schön R., Schade W. Species differences in biotransformation of 17α-cyanomethylestradiol 3-methyl ether // Steroids. 1980. Vol. 36. No. 2. pp. 131-147.
ГОСТ со всеми авторами (до 50) Скопировать
Hobe G., Schön R., Schade W. Species differences in biotransformation of 17α-cyanomethylestradiol 3-methyl ether // Steroids. 1980. Vol. 36. No. 2. pp. 131-147.
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TY - JOUR
DO - 10.1016/0039-128x(80)90013-6
UR - https://doi.org/10.1016/0039-128x(80)90013-6
TI - Species differences in biotransformation of 17α-cyanomethylestradiol 3-methyl ether
T2 - Steroids
AU - Hobe, G
AU - Schön, R.
AU - Schade, W
PY - 1980
DA - 1980/08/01
PB - Elsevier
SP - 131-147
IS - 2
VL - 36
PMID - 7444986
SN - 0039-128X
SN - 1878-5867
ER -
BibTex |
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@article{1980_Hobe,
author = {G Hobe and R. Schön and W Schade},
title = {Species differences in biotransformation of 17α-cyanomethylestradiol 3-methyl ether},
journal = {Steroids},
year = {1980},
volume = {36},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/0039-128x(80)90013-6},
number = {2},
pages = {131--147},
doi = {10.1016/0039-128x(80)90013-6}
}
MLA
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Hobe, G., et al. “Species differences in biotransformation of 17α-cyanomethylestradiol 3-methyl ether.” Steroids, vol. 36, no. 2, Aug. 1980, pp. 131-147. https://doi.org/10.1016/0039-128x(80)90013-6.
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