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Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents
Publication type: Journal Article
Publication date: 1992-10-01
scimago Q1
wos Q1
SJR: 0.988
CiteScore: 10.1
Impact factor: 5.2
ISSN: 03785173, 18733476
Pharmaceutical Science
Abstract
The effects of the cationic, non-antibiotic antimicrobial agents chlorhexidine gluconate, dequalinium chloride, cetrimide and cetylpyridinium chloride on the adherence of Candida albicans blastospores (MEN and oral clinical isolates, exponential and stationary growth phases) to human buccal epithelial cells in vitro were examined using light microscopy. All agents expressed significant anti-adherence activities at concentrations both greater and less than the minimum inhibitory concentration. In all cases, the anti-adherence effects were observed following treatment (30 min, 37°C) of either buccal epithelial cells or blastospores. In addition, the majority of treatments significantly increased the number of buccal epithelial cells from from adherent C. albicans. These observations may be useful in the prophylaxis of oral candidosis in prone individuals.
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FOWLER S. C., David L. Jones D. Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents // International Journal of Pharmaceutics. 1992. Vol. 86. No. 2-3. pp. 193-199.
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FOWLER S. C., David L. Jones D. Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents // International Journal of Pharmaceutics. 1992. Vol. 86. No. 2-3. pp. 193-199.
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TY - JOUR
DO - 10.1016/0378-5173(92)90197-a
UR - https://doi.org/10.1016/0378-5173(92)90197-a
TI - Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents
T2 - International Journal of Pharmaceutics
AU - FOWLER, STEPHEN C.
AU - David L. Jones, David
PY - 1992
DA - 1992/10/01
PB - Elsevier
SP - 193-199
IS - 2-3
VL - 86
SN - 0378-5173
SN - 1873-3476
ER -
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BibTex (up to 50 authors)
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@article{1992_FOWLER,
author = {STEPHEN C. FOWLER and David David L. Jones},
title = {Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents},
journal = {International Journal of Pharmaceutics},
year = {1992},
volume = {86},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/0378-5173(92)90197-a},
number = {2-3},
pages = {193--199},
doi = {10.1016/0378-5173(92)90197-a}
}
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MLA
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FOWLER, STEPHEN C., and David David L. Jones. “Modified adherence of Candida albicans to human buccal epithelial cells in vitro following treatment with cationic, non-antibiotic antimicrobial agents.” International Journal of Pharmaceutics, vol. 86, no. 2-3, Oct. 1992, pp. 193-199. https://doi.org/10.1016/0378-5173(92)90197-a.