Synthesis of 17-[18F]fluoro-5-methylheptadecanoic acid

Publication typeJournal Article
Publication date1992-06-01
General Engineering
Abstract
5-Methyl-branched fatty acid, which was designed for less hindrance by the methyl group in heart uptake as compared with the 3-methyl-branched fatty acid, was labeled with fluorine-18 at the ω-position. The total time of synthesis, including HPLC purification and emulsification was 85–100 min from the start of reactive 18 F - production. The decay-corrected isolated yields of 17-[ 18 F]fluoro-5-methyl-heptadecanoic acid after emulsification were 10–17% and the radiochemical purities were >97%.
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TAKAHASHI T., Ido T., Iwata R. Synthesis of 17-[18F]fluoro-5-methylheptadecanoic acid // International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes. 1992. Vol. 43. No. 6. pp. 822-824.
GOST all authors (up to 50) Copy
TAKAHASHI T., Ido T., Iwata R. Synthesis of 17-[18F]fluoro-5-methylheptadecanoic acid // International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes. 1992. Vol. 43. No. 6. pp. 822-824.
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RIS Copy
TY - JOUR
DO - 10.1016/0883-2889(92)90251-9
UR - https://doi.org/10.1016/0883-2889(92)90251-9
TI - Synthesis of 17-[18F]fluoro-5-methylheptadecanoic acid
T2 - International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes
AU - TAKAHASHI, Toshihiro
AU - Ido, Tatsuo
AU - Iwata, R
PY - 1992
DA - 1992/06/01
PB - Elsevier
SP - 822-824
IS - 6
VL - 43
SN - 0883-2889
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{1992_TAKAHASHI,
author = {Toshihiro TAKAHASHI and Tatsuo Ido and R Iwata},
title = {Synthesis of 17-[18F]fluoro-5-methylheptadecanoic acid},
journal = {International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes},
year = {1992},
volume = {43},
publisher = {Elsevier},
month = {jun},
url = {https://doi.org/10.1016/0883-2889(92)90251-9},
number = {6},
pages = {822--824},
doi = {10.1016/0883-2889(92)90251-9}
}
MLA
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MLA Copy
TAKAHASHI, Toshihiro, et al. “Synthesis of 17-[18F]fluoro-5-methylheptadecanoic acid.” International Journal of Radiation Applications and Instrumentation Part A Applied Radiation and Isotopes, vol. 43, no. 6, Jun. 1992, pp. 822-824. https://doi.org/10.1016/0883-2889(92)90251-9.