Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles
Publication type: Journal Article
Publication date: 2003-07-31
scimago Q1
wos Q1
SJR: 1.142
CiteScore: 11.3
Impact factor: 5.9
ISSN: 02235234, 17683254
PubMed ID:
12932907
Organic Chemistry
Drug Discovery
General Medicine
Pharmacology
Abstract
A series of 3-substituted 4-[5-(4-methoxy-2-nitrophenyl)-2-furfurylidene] amino-5-mercapto-1,2,4-triazoles (3) were synthesized. Aminomethylation of compounds 3 with formaldehyde and various secondary amines furnished Mannich bases 4 and 5. These compounds were characterized on the basis of IR, 1H-NMR, mass spectral data and elemental analysis. The newly synthesized compounds were screened for their anticancer activity against a panel of 60 cell lines derived from seven cancer types namely, lung, colon, melanoma, renal, ovarian, CNS and leukemia. Some of the compounds were slightly more potent.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
5
10
15
20
25
30
|
|
|
European Journal of Medicinal Chemistry
29 publications, 7.57%
|
|
|
Journal of Molecular Structure
27 publications, 7.05%
|
|
|
Journal of Heterocyclic Chemistry
19 publications, 4.96%
|
|
|
Medicinal Chemistry Research
13 publications, 3.39%
|
|
|
Phosphorus, Sulfur and Silicon and the Related Elements
13 publications, 3.39%
|
|
|
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
12 publications, 3.13%
|
|
|
Journal of Enzyme Inhibition and Medicinal Chemistry
12 publications, 3.13%
|
|
|
Acta Crystallographica Section E Structure Reports Online
9 publications, 2.35%
|
|
|
Molecules
9 publications, 2.35%
|
|
|
ChemistrySelect
9 publications, 2.35%
|
|
|
Molecular Diversity
6 publications, 1.57%
|
|
|
Russian Journal of Organic Chemistry
6 publications, 1.57%
|
|
|
Arabian Journal of Chemistry
5 publications, 1.31%
|
|
|
Bioorganic and Medicinal Chemistry Letters
5 publications, 1.31%
|
|
|
RSC Advances
5 publications, 1.31%
|
|
|
Polyhedron
4 publications, 1.04%
|
|
|
Bioorganic and Medicinal Chemistry
4 publications, 1.04%
|
|
|
Chemical Biology and Drug Design
4 publications, 1.04%
|
|
|
Applied Organometallic Chemistry
4 publications, 1.04%
|
|
|
Synthetic Communications
4 publications, 1.04%
|
|
|
Polycyclic Aromatic Compounds
4 publications, 1.04%
|
|
|
Synthesis
4 publications, 1.04%
|
|
|
Journal of Chemical Research
3 publications, 0.78%
|
|
|
Journal of the Iranian Chemical Society
3 publications, 0.78%
|
|
|
Monatshefte fur Chemie
3 publications, 0.78%
|
|
|
Chemistry of Natural Compounds
3 publications, 0.78%
|
|
|
Journal of Chemical Sciences
3 publications, 0.78%
|
|
|
Journal of Chemical Crystallography
3 publications, 0.78%
|
|
|
Journal of the Korean Chemical Society
3 publications, 0.78%
|
|
|
Bulletin of the Korean Chemical Society
3 publications, 0.78%
|
|
|
5
10
15
20
25
30
|
Publishers
|
20
40
60
80
100
120
|
|
|
Elsevier
113 publications, 29.5%
|
|
|
Springer Nature
57 publications, 14.88%
|
|
|
Wiley
56 publications, 14.62%
|
|
|
Taylor & Francis
50 publications, 13.05%
|
|
|
Pleiades Publishing
12 publications, 3.13%
|
|
|
International Union of Crystallography (IUCr)
11 publications, 2.87%
|
|
|
MDPI
11 publications, 2.87%
|
|
|
Royal Society of Chemistry (RSC)
8 publications, 2.09%
|
|
|
Bentham Science Publishers Ltd.
6 publications, 1.57%
|
|
|
Georg Thieme Verlag KG
6 publications, 1.57%
|
|
|
American Chemical Society (ACS)
5 publications, 1.31%
|
|
|
King Saud University
5 publications, 1.31%
|
|
|
Hindawi Limited
5 publications, 1.31%
|
|
|
SAGE
4 publications, 1.04%
|
|
|
Korean Chemical Society
3 publications, 0.78%
|
|
|
The Japan Institute of Heterocyclic Chemistry
3 publications, 0.78%
|
|
|
AIP Publishing
2 publications, 0.52%
|
|
|
Akademizdatcenter Nauka
2 publications, 0.52%
|
|
|
Pharmaceutical Society of Korea
2 publications, 0.52%
|
|
|
IOP Publishing
2 publications, 0.52%
|
|
|
European Journal of Chemistry
2 publications, 0.52%
|
|
|
Scientific Research Publishing
2 publications, 0.52%
|
|
|
Walter de Gruyter
2 publications, 0.52%
|
|
|
Asian Journal of Chemistry
2 publications, 0.52%
|
|
|
Beilstein-Institut
1 publication, 0.26%
|
|
|
Japan Society for Analytical Chemistry
1 publication, 0.26%
|
|
|
National Library of Serbia
1 publication, 0.26%
|
|
|
Pharmaceutical Society of Japan
1 publication, 0.26%
|
|
|
The Electrochemical Society
1 publication, 0.26%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 0.26%
|
|
|
20
40
60
80
100
120
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
383
Total citations:
383
Citations from 2024:
20
(5.22%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Shivarama Holla B. et al. Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles // European Journal of Medicinal Chemistry. 2003. Vol. 38. No. 7-8. pp. 759-767.
GOST all authors (up to 50)
Copy
Shivarama Holla B., Veerendra B., Shivananda M., Boja Poojary B. Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles // European Journal of Medicinal Chemistry. 2003. Vol. 38. No. 7-8. pp. 759-767.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/S0223-5234(03)00128-4
UR - https://doi.org/10.1016/S0223-5234(03)00128-4
TI - Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles
T2 - European Journal of Medicinal Chemistry
AU - Shivarama Holla, B.
AU - Veerendra, B.
AU - Shivananda, M.K.
AU - Boja Poojary, Boja
PY - 2003
DA - 2003/07/31
PB - Elsevier
SP - 759-767
IS - 7-8
VL - 38
PMID - 12932907
SN - 0223-5234
SN - 1768-3254
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2003_Shivarama Holla,
author = {B. Shivarama Holla and B. Veerendra and M.K. Shivananda and Boja Boja Poojary},
title = {Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles},
journal = {European Journal of Medicinal Chemistry},
year = {2003},
volume = {38},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/S0223-5234(03)00128-4},
number = {7-8},
pages = {759--767},
doi = {10.1016/S0223-5234(03)00128-4}
}
Cite this
MLA
Copy
Shivarama Holla, B., et al. “Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles.” European Journal of Medicinal Chemistry, vol. 38, no. 7-8, Jul. 2003, pp. 759-767. https://doi.org/10.1016/S0223-5234(03)00128-4.