Crizotinib: A comprehensive profile

Publication typeBook Chapter
Publication date2023-02-02
SJR
CiteScore18.2
Impact factor
ISSN18715125, 00995428
Abstract
Crizotinib, approved in 2011, was the first approved inhibitor targeting anaplastic lymphoma kinase (ALK) It used for treatment of the patients with metastatic non-small cell lung cancer (NSCLC) that is anaplastic lymphoma kinase (ALK) positive. This chapter provides a complete review of crizotinib including nomenclature, physiochemical properties, methods of preparation, identification techniques and various qualitative and quantitative analytical techniques as well as pharmacology of crizotinib. In addition, the chapter also includes review of several methods for separation of crizotinib using chromatographic techniques.
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GOST Copy
Abdelgalil A. A., Alkahtani H. M. Crizotinib: A comprehensive profile // Profiles of Drug Substances, Excipients and Related Methodology. 2023. Vol. 48. pp. 39-69.
GOST all authors (up to 50) Copy
Abdelgalil A. A., Alkahtani H. M. Crizotinib: A comprehensive profile // Profiles of Drug Substances, Excipients and Related Methodology. 2023. Vol. 48. pp. 39-69.
RIS |
Cite this
RIS Copy
TY - GENERIC
DO - 10.1016/bs.podrm.2022.11.002
UR - https://doi.org/10.1016/bs.podrm.2022.11.002
TI - Crizotinib: A comprehensive profile
T2 - Profiles of Drug Substances, Excipients and Related Methodology
AU - Abdelgalil, Ahmed A
AU - Alkahtani, Hamad M.
PY - 2023
DA - 2023/02/02
PB - Elsevier
SP - 39-69
VL - 48
PMID - 37061275
SN - 1871-5125
SN - 0099-5428
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@incollection{2023_Abdelgalil,
author = {Ahmed A Abdelgalil and Hamad M. Alkahtani},
title = {Crizotinib: A comprehensive profile},
publisher = {Elsevier},
year = {2023},
volume = {48},
pages = {39--69},
month = {feb}
}