Vitamin B6 status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial
Sergen Belen
1, 2
,
Nadine Patt
3
,
Marie Kupjetz
1
,
Per M. Ueland
4
,
Adrian McCann
4
,
Roman Gonzenbach
3
,
Jens Bansi
3, 5
,
Philipp Zimmer
1
3
Department of Neurology, Rehabilitation Centre Valens, Clinics of Valens, Valens, Switzerland
|
4
BEVITAL AS, Bergen, Norway
|
Publication type: Journal Article
Publication date: 2025-06-01
scimago Q1
wos Q1
SJR: 2.111
CiteScore: 12.6
Impact factor: 6.9
ISSN: 00029165, 19383207
Abstract
BackgroundLow circulating concentrations of B vitamins are linked to various chronic and neurodegenerative diseases. Notably, pyridoxal 5'-phosphate (vitamin B6) deficiency is linked to altered inflammatory responses and cellular immune function, both critical in multiple sclerosis (MS). Nevertheless, most MS research has focused on folate (vitamin B9) and vitamin B12, leaving other B vitamins understudied.
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Belen S. et al. Vitamin B6 status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial // American Journal of Clinical Nutrition. 2025. Vol. 121. No. 6. pp. 1403-1414.
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Belen S., Patt N., Kupjetz M., Ueland P. M., McCann A., Gonzenbach R., Bansi J., Zimmer P. Vitamin B6 status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial // American Journal of Clinical Nutrition. 2025. Vol. 121. No. 6. pp. 1403-1414.
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TY - JOUR
DO - 10.1016/j.ajcnut.2025.04.014
UR - https://linkinghub.elsevier.com/retrieve/pii/S000291652500200X
TI - Vitamin B6 status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial
T2 - American Journal of Clinical Nutrition
AU - Belen, Sergen
AU - Patt, Nadine
AU - Kupjetz, Marie
AU - Ueland, Per M.
AU - McCann, Adrian
AU - Gonzenbach, Roman
AU - Bansi, Jens
AU - Zimmer, Philipp
PY - 2025
DA - 2025/06/01
PB - Elsevier
SP - 1403-1414
IS - 6
VL - 121
SN - 0002-9165
SN - 1938-3207
ER -
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@article{2025_Belen,
author = {Sergen Belen and Nadine Patt and Marie Kupjetz and Per M. Ueland and Adrian McCann and Roman Gonzenbach and Jens Bansi and Philipp Zimmer},
title = {Vitamin B6 status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial},
journal = {American Journal of Clinical Nutrition},
year = {2025},
volume = {121},
publisher = {Elsevier},
month = {jun},
url = {https://linkinghub.elsevier.com/retrieve/pii/S000291652500200X},
number = {6},
pages = {1403--1414},
doi = {10.1016/j.ajcnut.2025.04.014}
}
Cite this
MLA
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Belen, Sergen, et al. “Vitamin B6 status is related to disease severity and modulated by endurance exercise in individuals with multiple sclerosis: a secondary analysis of a randomized controlled trial.” American Journal of Clinical Nutrition, vol. 121, no. 6, Jun. 2025, pp. 1403-1414. https://linkinghub.elsevier.com/retrieve/pii/S000291652500200X.