Open Access
Brain Behavior & Immunity - Health, volume 18, pages 100361
Roles of calcitonin gene-related peptide in the skin, and other physiological and pathophysiological functions
Yee Jeong Kim
1
,
Richard D. Granstein
1
Publication type: Journal Article
Publication date: 2021-12-01
Journal:
Brain Behavior & Immunity - Health
scimago Q1
SJR: 1.235
CiteScore: 8.5
Impact factor: 3.7
ISSN: 26663546
Nephrology
Abstract
Skin immunity is regulated by many mediator molecules. One is the neuropeptide calcitonin gene-related peptide (CGRP). CGRP has roles in regulating the function of components of the immune system including T cells, B cells, dendritic cells (DCs), endothelial cells (ECs), and mast cells (MCs). Herein we discuss actions of CGRP in mediating inflammatory and vascular effects in various cutaneous models and disorders.
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