Open Access
Nanotechnology-based drug delivery for central nervous system disorders
3
Viet Nam Sports Hospital, Ministry of Culture, Sports and Tourism, Hanoi 100000, Viet Nam.
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Publication type: Journal Article
Publication date: 2021-11-01
scimago Q1
wos Q1
SJR: 1.775
CiteScore: 12.8
Impact factor: 7.5
ISSN: 07533322, 19506007
PubMed ID:
34479020
General Medicine
Pharmacology
Abstract
Drug delivery to central nervous system (CNS) diseases is very challenging since the presence of the innate blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier that impede drug delivery. Among new strategies to overcome these limitations and successfully deliver drugs to the CNS, nanotechnology-based drug delivery platform, offers potential therapeutic approach for the treatment of some common neurological disorders like Alzheimer's disease, frontotemporal dementia, amyotrophic lateral sclerosis, Parkinson's disease, Huntington's disease. This review aimed to highlight advances in research on the development of nano-based therapeutics for their implications in therapy of CNS disorders. The challenges during clinical translation of nanomedicine from bench to bed side is also discussed.
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127
Total citations:
127
Citations from 2024:
73
(57.48%)
Cite this
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RIS |
BibTex
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GOST
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Nguyen T. et al. Nanotechnology-based drug delivery for central nervous system disorders // Biomedicine and Pharmacotherapy. 2021. Vol. 143. p. 112117.
GOST all authors (up to 50)
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Nguyen T., Nguyen T. H., Vo T. K., An T. T. T., Nguyen M. Nanotechnology-based drug delivery for central nervous system disorders // Biomedicine and Pharmacotherapy. 2021. Vol. 143. p. 112117.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.biopha.2021.112117
UR - https://doi.org/10.1016/j.biopha.2021.112117
TI - Nanotechnology-based drug delivery for central nervous system disorders
T2 - Biomedicine and Pharmacotherapy
AU - Nguyen, Thuy-Trang
AU - Nguyen, Thi Hong
AU - Vo, Tuong Kha
AU - An, Tran T. T.
AU - Nguyen, Minh
PY - 2021
DA - 2021/11/01
PB - Elsevier
SP - 112117
VL - 143
PMID - 34479020
SN - 0753-3322
SN - 1950-6007
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Nguyen,
author = {Thuy-Trang Nguyen and Thi Hong Nguyen and Tuong Kha Vo and Tran T. T. An and Minh Nguyen},
title = {Nanotechnology-based drug delivery for central nervous system disorders},
journal = {Biomedicine and Pharmacotherapy},
year = {2021},
volume = {143},
publisher = {Elsevier},
month = {nov},
url = {https://doi.org/10.1016/j.biopha.2021.112117},
pages = {112117},
doi = {10.1016/j.biopha.2021.112117}
}