Open Access
The role of N6-methyladenosine in macrophage polarization: A novel treatment strategy for non-alcoholic steatohepatitis
Publication type: Journal Article
Publication date: 2024-02-01
scimago Q1
wos Q1
SJR: 1.775
CiteScore: 12.8
Impact factor: 7.5
ISSN: 07533322, 19506007
PubMed ID:
38198958
General Medicine
Pharmacology
Abstract
RNA methylation modifications, as a widespread type of modification in eukaryotic cells, especially N6-methyladenosine (m6A), are associated with many activities in organisms, including macrophage polarization and progression of non-alcoholic steatohepatitis (NASH). Macrophages in the liver are of diverse origin and complex phenotype, exhibiting different functions in development of NASH. In the review, we discuss the functions of m6A and m6A-related enzymes in macrophage polarization. Furthermore, we retrospect the role of macrophage polarization in NASH. Finally, we discuss the prospects of m6A in macrophages and NASH, and provide guidance for the treatment of NASH.
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6
Total citations:
6
Citations from 2024:
6
(100%)
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GOST
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Wu J. et al. The role of N6-methyladenosine in macrophage polarization: A novel treatment strategy for non-alcoholic steatohepatitis // Biomedicine and Pharmacotherapy. 2024. Vol. 171. p. 116145.
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Wu J., Pan J., Zhou W., Zhou W., Ji G., Dang Y. The role of N6-methyladenosine in macrophage polarization: A novel treatment strategy for non-alcoholic steatohepatitis // Biomedicine and Pharmacotherapy. 2024. Vol. 171. p. 116145.
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RIS
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TY - JOUR
DO - 10.1016/j.biopha.2024.116145
UR - https://linkinghub.elsevier.com/retrieve/pii/S075333222400026X
TI - The role of N6-methyladenosine in macrophage polarization: A novel treatment strategy for non-alcoholic steatohepatitis
T2 - Biomedicine and Pharmacotherapy
AU - Wu, Jiaxuan
AU - Pan, Jiashu
AU - Zhou, Wenchang
AU - Zhou, Wenjun
AU - Ji, Guang
AU - Dang, Yanqi
PY - 2024
DA - 2024/02/01
PB - Elsevier
SP - 116145
VL - 171
PMID - 38198958
SN - 0753-3322
SN - 1950-6007
ER -
Cite this
BibTex (up to 50 authors)
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@article{2024_Wu,
author = {Jiaxuan Wu and Jiashu Pan and Wenchang Zhou and Wenjun Zhou and Guang Ji and Yanqi Dang},
title = {The role of N6-methyladenosine in macrophage polarization: A novel treatment strategy for non-alcoholic steatohepatitis},
journal = {Biomedicine and Pharmacotherapy},
year = {2024},
volume = {171},
publisher = {Elsevier},
month = {feb},
url = {https://linkinghub.elsevier.com/retrieve/pii/S075333222400026X},
pages = {116145},
doi = {10.1016/j.biopha.2024.116145}
}